NCT01087619Completed
Surgery for Primary Hyperparathyroidism (pHPT) in Patients Older Than 65 Years Compared With Follow-up
Primary Hyperparathyroidism in Patients Older Than 65 Years: A Prospective Randomized Trial of Surgical Treatment Compared With Follow-up
Source: ClinicalTrials.gov · Last updated 8 Apr 2026
Brief summary (registry, in English)
General consensus and contemporary guidelines, recommend surgery for primary hyperparathyroidism (pHPT)for all patients below the age of 50, for patients with pronounced hypercalcemia and for patients with organ complications to the disease (osteoporosis and decreased renal function). The purpose of this study is to determine if surgery for pHPT, is appropriate for patients with moderate to mild hypercalcemia older than 65 years of age. The hypothesis of the study is that surgery for pHPT in patients older than 65 years of age, and with mild hypercalcemia, will increase bone density and hence decrease future risk for fragility fractures compared to patients with follow-up only.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 102 (actual)
- First submitted
- 15 Mar 2010
- Start date
- 1 Aug 2010
- Primary completion date
- 30 Jun 2025
- Lead sponsor
- Region Skane
- Diseases
- Osteoporosis
- NCT number
- NCT01087619
What you commit to
- Study type: Interventional
- Participants enrolled: 102
- From 1 Aug 2010 to the primary completion date, 30 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- Serum level of ionized calcium \> 1.50 mmol/L
Other
- Z-score of Bone density \< -2.5 SD (regardless of site)
- Inability to understand given information or to comply with scheduled follow-up
- Symptoms of hypercalcaemia for which specific medical treatment has been prescribed
Who the study is looking for
- Primary Hyperparathyroidism
- No previous parathyroid surgery
- Sporadic disease
Age in the registry: 66 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Skåne University Hospital, Department of Surgery, Lund Coordinator of this site? Confirm its status | Lund | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.