NCT01099982Recruiting
Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease, Effects of Mechanical Unloading on Myocardial Function and Structure in Humans
Source: ClinicalTrials.gov · Last updated 13 Aug 2026
Brief summary (registry, in English)
Hypothesis: Tissue and serum samples collected from end-stage heart failure patients receiving left ventricular assist device implantation (LVAD) or heart transplantation will provide information regarding the basic science of heart disease. Tissue and serum samples collected from a limited numbers of "healthy controls" (donor grafts that were not utilized for heart transplantation) will serve as a comparator in research database projects. Design: This is a registry project; there are no investigational treatments, drug or procedures associated with participation in registry activities. This project is an organized functional data and tissue data gathering and storing (database) endeavor with specific focus on the functional, structural, and molecular aspects of heart failure. Data collection will not immediately influence the course of treatment for any patient.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 6 Apr 2010
- Start date
- 1 Sept 2008
- Primary completion date
- 31 Jan 2030
- Lead sponsor
- University of Utah
- Diseases
- Heart failure
- NCT number
- NCT01099982
What you commit to
- Study type: Observational
- Planned participants: 300
- From 1 Sept 2008 to the primary completion date, 31 Jan 2030
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Neither patient nor patient representative understands spoken English
- Neither patient nor patient's personal representative is willing to give written consent for participation.
Who the study is looking for
- \>18 years of age diagnosed with heart failure undergoing either LVAD implantation or heart transplantation
- 13 to 18 years of age, specifically, older children with heart failure whose body mass index is large enough to accommodate and LVAD
Age in the registry: 13 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Intermountain Medical Center Coordinator of this site? Confirm its status | Murray | United States | Recruiting |
| University of Utah Health Sciences Center Coordinator of this site? Confirm its status | Salt Lake City | United States | Recruiting |
| VA Salt Lake City Health Care System Coordinator of this site? Confirm its status | Salt Lake City | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.