NCT01113697Completed
Genetics of the Early and Late Response to Allergen Challenge
Molecular Mechanisms Involved in the Early and Late Responses to Allergen Challenge, in Asthmatic and Allergic Rhinitis Cohorts
Source: ClinicalTrials.gov · Last updated 6 Dec 2023
Brief summary (registry, in English)
The investigators are investigating the early and late responses to allergen challenge. The research participants who the investigators will study (from three cohorts) will be part of independently-approved studies involving allergen challenge. Due to the uniqueness of the cohorts for novel genetic study, it is logical that the investigators should initially undertake hypothesis-generating experiments. The investigators will obtain blood samples from the participants, both pre-challenge and post-challenge. The investigators will determine gene expression and protein differences between these samples, and investigate if there are inherited genetic differences between individuals that may predict their specific responses to allergens.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 520 (actual)
- First submitted
- 28 Apr 2010
- Start date
- Aug 2009
- Primary completion date
- Dec 2023
- Lead sponsor
- University of British Columbia
- Diseases
- Asthma
- NCT number
- NCT01113697
What you commit to
- Study type: Observational
- Participants enrolled: 520
- From Aug 2009 to the primary completion date, Dec 2023
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- participants will be healthy volunteer research subjects with allergic asthma, or
- participants will be volunteer research subjects with Western Red Cedar asthma, or
- participants will be healthy volunteer research subjects with allergic rhinitis (hay fever)
- all participants will be over 19 years of age so that they qualify for studies involving allergen challenge
Age in the registry: 19 years to 55 years · Sex: All · Accepts healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| McMaster University Coordinator of this site? Confirm its status | Hamilton | Canada | Unknown status |
| Queen's University Coordinator of this site? Confirm its status | Kingston | Canada | Unknown status |
| Laval University Coordinator of this site? Confirm its status | Québec | Canada | Unknown status |
| University of Saskatchewan Coordinator of this site? Confirm its status | Saskatoon | Canada | Unknown status |
| University of British Columbia Coordinator of this site? Confirm its status | Vancouver | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.