NCT01118130Completed
Pharmacogenomics of Drug Safety in Multiple Sclerosis
Canadian Pharmacogenomics Network for Drug Safety: Genetic Factors Associated With Multiple Sclerosis Treatment
Source: ClinicalTrials.gov · Last updated 14 Jan 2026
Brief summary (registry, in English)
To investigate whether genotypic differences can be identified between MS patients developing 'liver injury' (defined as ALT levels five times the upper normal limit and above) compared to those not developing liver injury after exposure to beta-interferon for MS.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 4 May 2010
- Start date
- Jun 2010
- Primary completion date
- May 2025
- Lead sponsor
- University of British Columbia
- Diseases
- Multiple sclerosis
- NCT number
- NCT01118130
What you commit to
- Study type: Observational
- Planned participants: 300
- From Jun 2010 to the primary completion date, May 2025
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- primary-progressive MS
- an elevated liver test result within 6 months of starting beta-interferon treatment
- presence of a co-morbidity that is a known risk-factor for liver injury
Who the study is looking for
- definite MS (Poser or McDonald criteria)
- relapsing-remitting or secondary-progressive disease course
- Prescribed a beta-interferon as their immunomodulatory drug for MS
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dalhousie MS Research Unit Coordinator of this site? Confirm its status | Halifax | Canada | Unknown status |
| London Health Sciences Centre MS clinic Coordinator of this site? Confirm its status | London | Canada | Unknown status |
| Hôpital Notre-Dame MS clinic Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| MS Clinic UBC Hospital Coordinator of this site? Confirm its status | Vancouver | Canada | Unknown status |
| Winnipeg Health Sciences Centre Coordinator of this site? Confirm its status | Winnipeg | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.