NCT01161953Completed
Genetic Epidemiology of Primary Biliary Cirrhosis (PBC)
Understanding the Genetic Predisposition to the Development of Primary Biliary Cirrhosis (PBC).
Source: ClinicalTrials.gov · Last updated 29 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Primary Biliary Cirrhosis (PBC) is a progressive liver disorder of unknown cause. Current evidence suggests that genes, the genetic material we inherit from our parents, in combination with environmental factors, likely play an important role in the development of PBC. This study is being done to investigate whether genes make people more likely to develop PBC. Discovery of these proposed genes will help us better understand how PBC developes, and subsequently, to apply new approaches for its prevention, diagnosis and treatment.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1500 (estimated)
- First submitted
- 12 Jul 2010
- Start date
- 1 Mar 2002
- Primary completion date
- 31 Jul 2025
- Lead sponsor
- Mayo Clinic
- Diseases
- Primary biliary cholangitis
- NCT number
- NCT01161953
What you commit to
- Study type: Observational
- Planned participants: 1500
- From 1 Mar 2002 to the primary completion date, 31 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Individuals with no history of PBC or those unable to provide consent.
Who the study is looking for
- Men and women between the ages of 18-90 who have a history of PBC.
- PBC patients who have undergone a liver transplant are eligible.
- Family members (1st degree relatives) of enrolled PBC patients are eligible.
Age in the registry: 18 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.