NCT01176578Active, not recruiting
Exercise Endothelial Progenitor Cells (EPCs) and Type 2 Diabetes
Exercise Training, CACs, and Vascular Function in Older Veterans With IGT (Impaired Glucose Tolerance)
Source: ClinicalTrials.gov · Last updated 19 Sept 2025
Brief summary (registry, in English)
The discovery of the role of endothelial progenitor cells (EPCs) and their involvement in the cardiovascular complications of type 2 diabetes (T2DM) would quickly have a significant impact on the millions of Americans who have T2DM. This project is designed to 1) determine the mechanisms underlying EPC dysfunction in older, sedentary adults with T2DM compared those with normal glucose metabolism and impaired glucose metabolism, and 2) determine if aerobic exercise training is an efficacious therapy for EPC dysfunction in T2DM, and whether improvement in EPC number and function translates to improved endothelial function, increased capillarization, and improved glucose metabolism in T2DM.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 5 Aug 2010
- Start date
- Jul 2011
- Primary completion date
- 31 Dec 2021
- Lead sponsor
- Baltimore VA Medical Center
- Diseases
- Type 2 diabetes
- NCT number
- NCT01176578
What you commit to
- Study type: Interventional
- Planned participants: 70
- From Jul 2011 to the primary completion date, 31 Dec 2021
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of heart disease or stroke
- Cancer
- Poorly controlled hypertension or dyslipidemia
- Kidney or Liver diseases
Who the study is looking for
- Age 50-80
- Non-smoker
- If woman, postmenopausal \>1 year
Age in the registry: 50 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Baltimore VA Medical Center Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.