NCT01177618Completed
Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study
Genetic Epidemiology of Severe, Early-Onset Chronic Obstructive Pulmonary Disease
Source: ClinicalTrials.gov · Last updated 21 Oct 2026
Brief summary (registry, in English)
Chronic obstructive pulmonary disease (COPD) is often caused by cigarette smoking, but genetic predisposition also influences COPD susceptibility. The purpose of this study is to identify genetic factors that predispose some individuals to develop COPD.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 2000 (estimated)
- First submitted
- 6 Aug 2010
- Start date
- Jul 1994
- Primary completion date
- Sept 2026
- Lead sponsor
- Brigham and Women's Hospital
- Diseases
- COPD
- NCT number
- NCT01177618
What you commit to
- Study type: Observational
- Planned participants: 2000
- From Jul 1994 to the primary completion date, Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any previous lung surgery including lung transplant or lung reduction volume surgery (LVRS); unless prior Pulmonary Function Tests are available
Other illness
- Other chronic lung diseases in participants with COPD (except asthma)
Other
- Severe alpha-1 antitrypsin deficiency
- Pregnant
Who the study is looking for
- Early onset of COPD in individuals younger than 53 years old
- Spirometry results that are indicative of severe COPD (FEV1 \< 40% predicted)
- Physician-diagnosed COPD
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Brigham and Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.