NCT01508962Active, not recruiting
PRE-Symptomatic Studies in Amyotrophic Lateral Sclerosis
Source: ClinicalTrials.gov · Last updated 20 Mar 2026
Brief summary (registry, in English)
The goal of PRESS-ALS is to study the earliest manifestations of disease in people with early ALS in whom some areas of the body are not yet affected.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 9 Jan 2012
- Start date
- Nov 2013
- Primary completion date
- Dec 2037
- Lead sponsor
- University of Miami
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT01508962
What you commit to
- Study type: Observational
- Planned participants: 100
- From Nov 2013 to the primary completion date, Dec 2037
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- ALS group:
- Subject is a male or female, aged at least 18 years.
- Subject is affected with ALS (familial or sporadic).
- Subject has at least one limb in which there is no symptomatic upper and lower motor neuron dysfunction.
- Subject is willing and able to comply with all study procedures.
- Subject agrees to provide signed and dated informed consent form.
- Control group:
- Subject is a male or female, aged at least 18 years.
- Subject is not affected with ALS or an ALS-related disorder.
- Subject does not have a family history (i.e., at least 2 biological relatives) of ALS or an ALS-related disorder.
- Subject is willing and able to comply with all study procedures.
- Subject agrees to provide signed and dated informed consent form.
- Exclusion Criterion
- Any condition or situation which, in the PI's opinion, could confound the biomarker data or may interfere significantly with the individual's participation and compliance with the study protocol, including but not limited to neurological, psychological and/or medical conditions (e.g., multiple sclerosis, neuropathy, myelopathy).
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Miami Coordinator of this site? Confirm its status | Miami | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.