NCT01719016Active, not recruiting
Improvement Assessment of Coronary Flow Dysfunction Using Fundamental Fluid Dynamics
Source: ClinicalTrials.gov · Last updated 4 Sept 2026
Brief summary (registry, in English)
Diagnosis of relative contributions of large artery blockages and microvascular blockages is very much needed in the treatment of coronary artery disease. In order to achieve this, two novel parameters, pressure drop coefficient (CDP), which combines flow and pressure readings and Lesion flow coefficient (LFC), which combines anatomical details of the lesion with pressure and flow readings, are being investigated.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 68 (actual)
- First submitted
- 29 Oct 2012
- Start date
- Aug 2010
- Primary completion date
- 30 Jul 2027
- Lead sponsor
- University of Cincinnati
- Diseases
- Coronary artery disease
- NCT number
- NCT01719016
What you commit to
- Study type: Observational
- Participants enrolled: 68
- From Aug 2010 to the primary completion date, 30 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of type II heparin-induced thrombocytopenia.
- Significant co-morbid condition that is medically unstable and would make coronary angiography prohibitive or contraindicated.
Lab values
- Left ventricular ejection fraction less the 25% determined by gated SPECT imaging
- Non-dialysis dependent chronic kidney disease with baseline serum creatinine greater than 2.5 gm/dL.
Other
- Pregnant women.
- Incapacitated for Consent
Who the study is looking for
- 18 years of age or above
- Patients referred to a stress test by a Cardiologist
- Acute Chest pain, as per patient input.
- Risk Assessment with prior test results and/or previous history of known chronic stable CAD.
- Borderline or discordant stress testing where obstructive CAD remains a concern.
- New or worsening symptoms- Abnormal coronary angiography or abnormal prior stress imaging study.
- Coronary stenosis or anatomic abnormality of uncertain significance.
- In absence of reliable diagnostic information from another imaging modality.
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cincinnati Veteran Affairs Medical Center Coordinator of this site? Confirm its status | Cincinnati | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.