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NCT01722383Active, not recruiting

What Are the Determinations of Adult Progressive CKD? The Renal Impairment In Secondary Care (RIISC) Study

Source: ClinicalTrials.gov · Last updated 5 Oct 2016

Brief summary (registry, in English)

Chronic kidney disease (CKD) affects up to 16% of the adult population and is associated with significant morbidity and mortality. People at highest risk from progressive CKD are defined by a sustained decline in estimated glomerular filtration rate (eGFR) and/or the presence of significant albuminuria/proteinuria. Accurate mapping of the bio-clinical determinants of this group will enable improved risk stratification and direct the development of better targeted management for people with CKD. To address these requirements we have established the Renal Impairment in Secondary Care (RIISC) study; RIISC is enrolling a cohort of patients at high risk from progressive CKD and compiling a comprehensive and detailed bio-clinical phenotype, including vascular and oral health phenotyping, at enrolment and on subsequent follow-up.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
932 (actual)
First submitted
2 Nov 2012
Start date
Oct 2010
Primary completion date
Dec 2025
Lead sponsor
University Hospital Birmingham NHS Foundation Trust
NCT number
NCT01722383

What you commit to

  • Study type: Observational
  • Participants enrolled: 932
  • From Oct 2010 to the primary completion date, Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • renal replacement therapy

Other

  • immunosuppression

Who the study is looking for

  • Decline of eGFR of ≥5mls/min/year or ≥10mls/min/5years
  • and/or urinary albumin-creatinine ration (ACR) ≥70 mg/mmol on three occasions
  • and/or CKD 4 or 5 (pre-dialysis)

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Queen Elizabeth Hospital Birmingham
Coordinator of this site? Confirm its status
BirminghamUnited KingdomUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.