NCT01728571Active, not recruiting
LungVITamin D and OmegA-3 Trial (lungVITAL)
LungVITamin D and OmegA-3 Trial
Source: ClinicalTrials.gov · Last updated 7 Aug 2026
Brief summary (registry, in English)
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is an ongoing randomized clinical trial in 25,871 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil, 1 gram) reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses. This ancillary study is being conducted among participants in VITAL and will examine whether vitamin D or fish oil reduces respiratory morbidity, including COPD and asthma exacerbations, the risk of pneumonia, and airflow obstruction/decline of pulmonary function; and whether either of these interventions improves asthma control.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 25871 (actual)
- First submitted
- 25 Oct 2012
- Start date
- 1 Jul 2010
- Primary completion date
- 11 Oct 2018
- Lead sponsor
- Brigham and Women's Hospital
- NCT number
- NCT01728571
What you commit to
- Study type: Interventional
- Participants enrolled: 25871
- From 1 Jul 2010 to the primary completion date, 11 Oct 2018
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- This study is open to all VITAL participants (NCT 01169259). Population includes men 50 years of age or older and women 55 years of age or older in the United States
- Participants who live in selected metropolitan areas of the U.S. (where we set up the infrastructure for clinic or home visits), are eligible for pulmonary function measurements.
Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Brigham and Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
Related publications
- Vitamin D Supplementation, Chronic Obstructive Lung Disease and Asthma Exacerbations, and Lung Function Decline.J Nutr · 2025 · PMID 39922497
- Lung VITAL: Rationale, design, and baseline characteristics of an ancillary study evaluating the effects of vitamin D and/or marine omega-3 fatty acid supplements on acute exacerbations of chronic respiratory disease, asthma control, pneumonia and lung function in adults.Contemp Clin Trials · 2016 · PMID 26784651
This page is information, not medical advice. Discuss any trial with your doctor.