NCT01737242Active, not recruiting
UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics Studies
Source: ClinicalTrials.gov · Last updated 12 Aug 2026
Brief summary (registry, in English)
The UKGPCS was set up to find genetic alterations which occur in patients who have prostate cancer. A man's risk of developing prostate cancer increases if he has a first-degree relative (father or brother) who was diagnosed with prostate cancer at a young age. This is why we are looking for men who are affected at a young age or who have a family history of prostate cancer, since it is more probable that these prostate cancers are due to an inherited genetic cause rather than an environmental cause. We also ask all men who come to the Royal Marsden Hospital to be treated for prostate cancer if they would like to take part in the study so that we can also look to see if we find genetic alterations in older men, and those who do not have a family history of prostate cancer.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 23826 (actual)
- First submitted
- 27 Nov 2012
- Start date
- Jan 1993
- Primary completion date
- Nov 2023
- Lead sponsor
- Institute of Cancer Research, United Kingdom
- Diseases
- Prostate cancer, Childhood cancers
- NCT number
- NCT01737242
What you commit to
- Study type: Observational
- Participants enrolled: 23826
- From Jan 1993 to the primary completion date, Nov 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Man with PrCa who is too ill to take part
Who the study is looking for
- Man with PrCa at any age at diagnosis at Royal Marsden NHS Foundation Trust
- Those outside the Royal Marsden NHS Foundation Trust with
- PrCa at or below 60 years at diagnosis
- PrCa in first-degree related pairs where one is ≤ 65 years at diagnosis
- PrCa at any age in a cluster with 3 or more cases
- Those able to understand the information sheet and give informed consent (language line is available for those who wish to have translation)
- Any unaffected relatives of men who are already taking part in the study
Sex: Male · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institute of Cancer Research and Royal Marsden Hospital Coordinator of this site? Confirm its status | Sutton | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.