NCT01737619Active, not recruiting
PET/CT and Lymph Node Mapping in Finding Lymph Node Metastasis in Patients With High-Risk Endometrial Cancer
Prospective Evaluation of Lymph Node Metastasis at the Time of Surgical Staging for High Risk Endometrial Cancer
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
This clinical trial studies positron emission tomography (PET)/computed tomography (CT) and lymph node mapping in finding lymph node metastasis in patients with endometrial cancer that is at high risk of spreading. A PET/CT scan is a procedure that combines the pictures from a PET scan and a CT scan, which are taken at the same time from the same machine. The combined scans give more detailed pictures of areas inside the body than either scan gives by itself. Lymph node mapping uses a radioactive dye, called indocyanine green solution, to identify lymph nodes that may contain cancer cells. PET/CT and sentinel lymph node mapping may be better ways than surgery to identify cancer in the lymph nodes.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 101 (actual)
- First submitted
- 27 Nov 2012
- Start date
- 3 Apr 2013
- Primary completion date
- 30 Apr 2025
- Lead sponsor
- M.D. Anderson Cancer Center
- Diseases
- Endometrial cancer
- NCT number
- NCT01737619
What you commit to
- Study type: Interventional
- Participants enrolled: 101
- From 3 Apr 2013 to the primary completion date, 30 Apr 2025
- 7 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Medical co-morbidities making surgery unsafe, as determined by the primary treating physician
Lab values
- Any contraindications to PET/CT or lymph node mapping (inability to control serum glucose to a value of =\< 200 mg/dl for fludeoxyglucose F-18 \[FDG\]-PET/CT)
- Baseline creatinine (necessary for imaging studies)
Other
- Does not meet histologic criteria
- Evidence of peritoneal or distant metastasis on preoperative imaging
Who the study is looking for
- Histologically confirmed high grade endometrial cancer including grade 3 endometroid, serous, clear cell, malignant mixed Mullerian tumor (MMMT) or any mixed tumor containing one of these cell types
- Patients with a grade 1/2 tumors and evidence of deep myometrial invasion or cervical involvement on preoperative imaging or physical exam
- Candidate for surgery
- No evidence of peritoneal disease on preoperative imaging
- Negative pregnancy test if of child-bearing age
- No preoperative treatment for endometrial cancer including radiation or chemotherapy
- Previous hormonal therapy is allowed
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Woman's Hospital of Texas Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| Lyndon Baines Johnson General Hospital Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| M D Anderson Cancer Center Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| MD Anderson Regional Care Center-Katy Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| MD Anderson Regional Care Center-Bay Area Coordinator of this site? Confirm its status | Nassau Bay | United States | Unknown status |
| MD Anderson Regional Care Center-Sugar Land Coordinator of this site? Confirm its status | Sugar Land | United States | Unknown status |
| MD Anderson Regional Care Center-The Woodlands Coordinator of this site? Confirm its status | The Woodlands | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.