NCT01745471Active, not recruiting
Adipose Tissue and Polycystic Ovary Syndrome (PCOS)(EIFFEL)
Adipose Tissue Angiogenesis in Polycystic Ovary Syndrome (PCOS)
Source: ClinicalTrials.gov · Last updated 3 Aug 2025
Brief summary (registry, in English)
The purpose of this study is to collect data to help understand why some women develop Polycystic Ovary Syndrome (PCOS) associated with decreased lower-body fat.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 36 (estimated)
- First submitted
- 5 Dec 2012
- Start date
- Dec 2012
- Primary completion date
- Apr 2024
- Lead sponsor
- AdventHealth Translational Research Institute
- Diseases
- Obesity
- NCT number
- NCT01745471
What you commit to
- Study type: Observational
- Planned participants: 36
- From Dec 2012 to the primary completion date, Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of oral contraceptives or hormone replacement therapy.
Other illness
- Untreated or symptomatic thyroid disease.
- Hypertension/ high blood pressure or are taking blood pressure medications
- History of drug or alcohol abuse (\> 3 drinks per day) in the last 5 years, or psychiatric disease prohibiting adherence to study protocol.
- History of cancer within the last 5 years.
- History of organ transplant.
- History of HIV, active Hepatitis B or C, or Tuberculosis.
- History of heart attack/ myocardial infarction.
Lab values
- Diagnosed with diabetes, or have a fasting blood sugar \> 126 mg/dL.
- Use of any medications known to influence glucose, fat and/or energy metabolism within the last 3 months (e.g., growth hormone therapy, glucocorticoids \[steroids\], etc.). Metformin for women with PCOS is allowed.
Other
- Male
- Women who are pregnant or lactating (breast feeding)
- Post-menopausal women
- Women with hysterectomy
- Impaired kidney or liver function, as evidenced by your blood work
- Presence of clinically significant abnormalities on EKG.
- Current smokers (smoking within the past 3 months)
Who the study is looking for
- Female
- Age \> 20 and \< 40
- Weight stable (change of less than 3 kg in the last 8 weeks)
- BMI \< 40 kg/m2 or \> 27 kg/m2
- Supplemental inclusion criteria for PCOS women:
- NIH criteria - confirmed by subjects' medical records.
Age in the registry: 20 years to 40 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Translational Research Institute for Metabolism and Diabetes Coordinator of this site? Confirm its status | Orlando | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.