NCT01781728CompletedPhase 2
Palliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma
Phase II Study to Evaluate Stereotactic Body Radiation Therapy For Palliative Management of Unresectable Recurrent or Residual Pancreatic or Periampullary Adenocarcinoma
Source: ClinicalTrials.gov · Last updated 20 Jul 2025
Brief summary (registry, in English)
The investigators are looking to see if a certain dose of stereotactic body radiation therapy (SBRT) may be a viable treatment option for recurrent or residual pancreatic or periampullary adenocarcinoma.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 48 (actual)
- First submitted
- 8 Aug 2012
- Start date
- 1 Jan 2013
- Primary completion date
- 1 Mar 2021
- Lead sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Diseases
- Pancreatic cancer
- NCT number
- NCT01781728
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 48
- From 1 Jan 2013 to the primary completion date, 1 Mar 2021
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- no concurrent malignancy other than melanoma
Other illness
- extensive metastatic disease
- no uncontrolled intercurrent illness
Other
- performance status of less than 70
- children are excluded form the study
- pregnant or breast feeding women are excluded
- women who are not post-menopausal and have a positive pregnancy test
- life expectancy of less than 3 months
Who the study is looking for
- 18 years of age or older
- Karnofsky Performance Status greater than or equal to 70%
- confirmed pancreatic or periampullary adenocarcinoma
- pancreatic or periampullary tumor less than 8.0 cm in greatest axial dimension
- Either:
- standard of care treatment for pancreatic cancer that included radiation therapy
- \* patients may be receiving continued chemotherapy post initial CRT. or
- standard of care treatment for pancreatic cancer that did not include radiation therapy \* patients must have attempted chemotherapy upon initial diagnosis
- acceptable organ and marrow function as determined by blood tests
- ability to understand and give consent
- must be a patient to be treated with SBRT only at Johns Hopkins Hospital
- life expectancy of greater than 3 months
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.