NCT01851642Recruiting
Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs
The Role of Conformational Diseases on Macrophage Function
Source: ClinicalTrials.gov · Last updated 6 Nov 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The purpose of this study is to look at how Alpha-1-antitrypsin (AAT) deficiency and Cystic Fibrosis (CF) affect white blood cells in the lungs, called macrophages, and their ability to work.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 220 (estimated)
- First submitted
- 25 Apr 2013
- Start date
- 9 Aug 2007
- Primary completion date
- 20 Jul 2032
- Lead sponsor
- University of Florida
- Diseases
- Cystic fibrosis
- NCT number
- NCT01851642
What you commit to
- Study type: Observational
- Planned participants: 220
- From 9 Aug 2007 to the primary completion date, 20 Jul 2032
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Large volume blood donation (\>200 ml or 7 ounces) within the previous 56 days (e.g. blood donation for the purposes of blood banking)
Other illness
- History of anemia requiring blood transfusions, erythropoietin supplementation, or iron supplementation within the past 36 months
- Clinically significant cardiac, hemostatic or neurological impairment or any other significant medical condition that, in the opinion of the investigator would affect subject safety (e.g., recent myocardial infarction, history of prolonged bleeding time, cerebral vascular accident, advanced cancer or uncontrolled medical condition)
- Psychiatric or cognitive disturbance or illness that would affect subject safety
Lab values
- Known hemoglobin \<12.5 g/dl within the past 90 days
Other
- Pregnancy or breastfeeding
- Weight \< 50 kg
- Systolic blood pressure \> 180 mmHg and/or diastolic blood pressure \>100 mmHg
- Poor venous access
- Current smoker
Who the study is looking for
- Signed informed consent
- Male or female 18 years of age or older
- Negative pregnancy test for women of childbearing potential
- Hemoglobin \>12.5 g/dl measured on the day of participation
- Negative urine nicotine test
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shands at the University of Florida Coordinator of this site? Confirm its status | Gainesville | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.