NCT01878344Active, not recruitingPhase 3
Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention
Effects of N-acetyl Cysteine on Major Cardiac and Cerebral Events in Patients Undergoing Primary Percutaneous Coronary Intervention Who Have Moderate to High Risk For Contrast Induced Nephropathy
Source: ClinicalTrials.gov · Last updated 20 May 2025
Brief summary (registry, in English)
The aim of this study is to evaluate the effects of N-acetyl cysteine on major cardiac and cerebral events in patients undergoing primary percutaneous coronary intervention who have moderate to high risk for contrast induced nephropathy. In a sub-group of patients coronary flow reserve will be evaluated.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 100 (actual)
- First submitted
- 12 Jun 2013
- Start date
- Jan 2013
- Primary completion date
- Jan 2018
- Lead sponsor
- Suleyman Demirel University
- Diseases
- Coronary artery disease
- NCT number
- NCT01878344
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 100
- From Jan 2013 to the primary completion date, Jan 2018
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of corticosteroids
- Blood pressure of \>180/100mmHg despite anti-hypertensive therapy
Other illness
- Infection
- Renal failure requiring dialysis
- Hepatic failure
- Allergy to NAC
- History of Asthma
- Malignancy
Age
- Patients \>18 years old with moderate to high risk for contrast induced nephropathy undergoing percutaneous coronary intervention
Other
- Low risk for contrast induced nephropathy (Mehran Score \<5)
- Use of nephrotoxic agents (NSAIDs, aminoglycosides,recent contrast injection...)
- Pregnancy, Lactation
- Chronic nitrate usage
- Leucocytosis,Thrombocytosis,Anemia
Who the study is looking for
- Patients with Acute ST Elevation Myocardial Infarction undergoing Primary Percutaneous Coronary intervention Who Have Moderate to High Risk For Contrast Induced Nephropathy (Mehran Score ≥5)
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Suleyman Demirel University Coordinator of this site? Confirm its status | Isparta | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.