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NCT01979796Withdrawn

Antismoking Effects of Electronic Cigarettes in Subjects With Schizophrenia and Their Potential Influence on Cognitive Functioning.

Antismoking Effects of Electronic Cigarettes in Subjects With Schizophrenia and Their Potential Influence on Cognitive Functioning: Design of a Randomized Trial. Smoking Cessation And Reduction In Schizophrenia (The SCARIS Study)

Source: ClinicalTrials.gov · Last updated 14 May 2026

Brief summary (registry, in English)

It is well established in studies across several countries that tobacco smoking is more prevalent among schizophrenic patients than the general population. Electronic cigarettes (e-cigarettes) are becoming increasingly popular with smokers worldwide. To date there are no large randomised trials of e-cigarettes in schizophrenic smokers. A well-designed trial is needed to compare efficacy and safety of these products in this special population.

Status (registry)
Withdrawn
Study type
Interventional
Enrollment
0 (actual)
First submitted
24 Oct 2013
Start date
Dec 2022
Primary completion date
Dec 2023
Lead sponsor
University of Catania
NCT number
NCT01979796

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • use of smokeless tobacco or nicotine replacement therapy

Other illness

  • current or recent (less than 1 yr) past history of alcohol and/or drug abuse

Other

  • pregnancy or breastfeeding.
  • other significant co-morbidities according to the Investigator's clinical assessment

Who the study is looking for

  • Schizophrenic subjects (according to DSM-IV-TR criteria) from throughout Sicily, (Italy), who smoke tobacco cigarettes, in stable phase of illness.
  • smoke ≥10 factory made cig/day, for at least the past five years
  • age 18-65 years
  • in good general health
  • not currently attempting to quit smoking or wishing to do so in the next 30 days (a specific test will be included to check their unwillingness to quit) 6 months
  • committed to follow the trial procedures.

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.