NCT02122666Completed
Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome
Modulating Physiologic Effects Of Phospholipid Metabolism In Obesity And Diabetes; AIM 4: Composition and Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome
Source: ClinicalTrials.gov · Last updated 26 Oct 2024
Brief summary (registry, in English)
The investigators previous research has suggested that lipid (fatty) composition in the muscle cells of mice plays a key role in their insulin sensitivity. The purpose of this study is to determine whether these specific fat signatures translate to humans by comparing the muscle of healthy patients to those with pre-diabetes, or "the metabolic syndrome".
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 27 (actual)
- First submitted
- 22 Apr 2014
- Start date
- Mar 2014
- Primary completion date
- 15 Feb 2024
- Lead sponsor
- Washington University School of Medicine
- Diseases
- Obesity
- NCT number
- NCT02122666
What you commit to
- Study type: Observational
- Participants enrolled: 27
- From Mar 2014 to the primary completion date, 15 Feb 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Control subjects
- Inclusion:
- Sedentary: No routine exercise, walking \<10,000 steps per day Age \>18 and \<65 Body Mass Index (BMI) \<32 Healthy by physical exam (patient is devoid of major acute or chronic illness) No significant abnormality in screening labs
- Exclusion:
- Currently on any significant prescription medications other than oral contraceptives in women Currently Pregnant Current Tobacco Use
- Subjects with the Metabolic Syndrome
- Inclusion:
- Sedentary: No routine exercise, walking \<10,000 steps per day Age \>18 and \<65 Body Mass Index (BMI) \>30
- Meet at least three of the following Adult Treatment Panel (ATP) III criteria for the metabolic syndrome:
- waist circumference \> or = 40 inches in men, \> or = 35 inches in women blood triglycerides \> or = 150 mg/dL blood HDL cholesterol \<40 mg/dL in men, \<50 in women blood pressure \> or = 130 mmHg systolic, or \> or = 85 mmHg diastolic fasting blood sugar \> or = 100 mg/dL
- Exclusion:
- Diagnosed with Type 2 diabetes, coronary artery disease, cancer, liver, lung, or kidney disease or any other major illness
- Currently on any significant prescription medications other than:
- oral contraceptives in women More than two standard medication for stage 1 hypertension in men or women (blood pressure 140-159/90-99) Currently Pregnant Current Tobacco Use
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Washington University School of Medicine Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.