NCT02132741Recruiting
Optical Coherence Tomography And NEphropathy: The OCTANE Study
Assessment of Retinal Vasculature Using Optical Coherence Tomography in Health, Hypertension & Chronic Kidney Disease.
Source: ClinicalTrials.gov · Last updated 13 May 2026
Brief summary (registry, in English)
Patients with high blood pressure (hypertension) and chronic kidney disease are at an increased risk of developing heart disease and strokes. Part of this risk is due to changes in the structure and function of the blood vessels throughout the body. It is thought that reducing high blood pressure and treating chronic kidney disease improves the structure and function of blood vessels but information on this is limited. Optical coherence tomography (OCT) is a method of looking at the blood vessels at the back of the eye. It is a simple, quick and non-invasive test that you may have previously had during a visit to the optician. The purpose of the study is to ascertain whether OCT is able to detect changes in the eye's blood vessels in patients with hypertension and chronic kidney disease compared to healthy individuals and also to see if any differences seen improve with treatment.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 29 Apr 2014
- Start date
- 16 May 2014
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- University of Edinburgh
- NCT number
- NCT02132741
What you commit to
- Study type: Observational
- Planned participants: 150
- From 16 May 2014 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Past or present drug or alcohol abuse including intravenous drug abuse at any time
- Patients with known eye disease, or previous eye surgery, or refractive error greater than +/- 6 dioptres.
Other illness
- Considered to be at high risk of HIV or hepatitis B
Age
- Subject is below the age of legal consent, or is mentally or legally incapacitated
Other
- The subject has donated blood (450 ml) within the last 4 weeks
- Participation in another clinical trial within 1 month
Who the study is looking for
- Male or female
- Age 18-80
- Body mass index ≤35
- For those with hypertension: BP ≥140/90 or on treatment for hypertension
- For those with CKD: CKD as defined by the Kidney Diseases Quality Initiative guidelines
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Edinburgh Coordinator of this site? Confirm its status | Edinburgh | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.