NCT02150889Active, not recruiting
Training Effects on Fuel Metabolism
Source: ClinicalTrials.gov · Last updated 8 Jan 2026
Brief summary (registry, in English)
The investigators are interested in how skeletal muscle processes fat and how this may affect insulin resistance. This is an important question since insulin resistance predates and predicts type 2 diabetes. The investigators are especially interested in learning about the effects of weight and training on insulin resistance. The investigators will study people before and after supervised aerobic or yoga training to identify differences in resting fat and sugar metabolism which may lead to differences in insulin resistance. The investigators will test these differences using stable isotopes, and the use of these stable isotopes is experimental. Overweight/Obese Group: Eight visits will be required at the University of Minnesota Clinical Research Unit. Four visits will be done before training (screen and 3 pre-training visits), 1 visit during the training, and 3 post-training visits will be done. In between, the training will take about 16 weeks and will be a supervised treadmill program. Lean/Trained Group: Four visits will be required at the University of Minnesota Clinical Research Unit (screen and 3 study visits).
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 64 (actual)
- First submitted
- 22 May 2014
- Start date
- 1 Jul 2014
- Primary completion date
- 30 Dec 2018
- Lead sponsor
- University of Minnesota
- Diseases
- Obesity
- NCT number
- NCT02150889
What you commit to
- Study type: Interventional
- Participants enrolled: 64
- From 1 Jul 2014 to the primary completion date, 30 Dec 2018
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- Insulin resistant based on screening oral glucose tolerance testing.
- generally healthy with normal fasting glucose levels (glucose ≤100 mg/dL).
Age
- Subjects 18 to 40 years of age.
- matched to age and gender
Other
- All subjects
- Subjects are capable of giving informed consent
- Overweight or obese
- BMI 25 to 40 kg/m2 inclusive
- Stable weight for at least 3 months (± 5 lbs.)
- Sedentary status (self-report \< 30 minutes/week regular exercise).
- Lean, physically active
- physically active subjects defined as 3-5 aerobic exercise sessions/week
Who the study is looking for
- All subjects
- Subjects 18 to 40 years of age.
- Subjects are capable of giving informed consent
- Overweight or obese
- Insulin resistant based on screening oral glucose tolerance testing.
- BMI 25 to 40 kg/m2 inclusive
- Stable weight for at least 3 months (± 5 lbs.)
- Sedentary status (self-report \< 30 minutes/week regular exercise).
- Lean, physically active
- physically active subjects defined as 3-5 aerobic exercise sessions/week
- matched to age and gender
- generally healthy with normal fasting glucose levels (glucose ≤100 mg/dL).
Age in the registry: 18 years to 40 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Minnesota Coordinator of this site? Confirm its status | Minneapolis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.