NCT02222844Recruiting
Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers
Source: ClinicalTrials.gov · Last updated 17 Oct 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Patients with suspected or proven sigmoid colon adenocarcinoma, eligible for curative treatment whose MRI can be reviewed prior to surgery and has no decision regarding radical treatment are eligible. Patient are randomised to the control arm which the standard care of preoperative CT imaging and subsequent discussion by the Multidisciplinary Team or the interventional arm which has the additional use of MRI imaging and subsequent discussion by the Multidisciplinary Team. Patients are followed up at 1 and 3 years together with QoL questionnaires.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 244 (estimated)
- First submitted
- 20 Aug 2014
- Start date
- Aug 2014
- Primary completion date
- Dec 2026
- Lead sponsor
- Imperial College London
- Diseases
- Colorectal cancer, Childhood cancers
- NCT number
- NCT02222844
What you commit to
- Study type: Interventional
- Planned participants: 244
- From Aug 2014 to the primary completion date, Dec 2026
- 16 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have severe co-morbidities or previous medical history that prevent the application of eventual chemo/radiotherapy
Other illness
- Have metastatic disease (including resectable liver metastases)
- Have a synchronous second malignancy
Lab values
- Are contraindicated for or have allergy to Buscopan (e.g. glaucoma, small or large bowel obstruction, GFR\<30)
Other
- Are contraindicated for MRI
Who the study is looking for
- Have a suspected or proven sigmoid colon adenocarcinoma
- Is eligible for curative treatment
- Has no irresectable metastatic disease
- MRI can be reviewed by an MDT prior to surgery
- Has no decision regarding radical treatment
- Have provided written informed consent to participate in the study
- Be aged 16 years or over
Age in the registry: 16 years to - · Sex: All · Does not accept healthy volunteers
Sites (16)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chesterfield Royal Coordinator of this site? Confirm its status | Chesterfield | United Kingdom | Recruiting |
| Leighton Hospital Coordinator of this site? Confirm its status | Crewe | United Kingdom | Recruiting |
| North Manchester General Hospital Coordinator of this site? Confirm its status | Crumpsall | United Kingdom | Recruiting |
| Harrogate District Hospital Coordinator of this site? Confirm its status | Harrogate | United Kingdom | Recruiting |
| Hinchingbrooke Hospital Coordinator of this site? Confirm its status | Huntingdon | United Kingdom | Recruiting |
| Maidstone Hospital Coordinator of this site? Confirm its status | Maidstone | United Kingdom | Recruiting |
| Queen Elizabeth The Queen Mother Hospital Coordinator of this site? Confirm its status | Margate | United Kingdom | Recruiting |
| St Mark's Hospital Coordinator of this site? Confirm its status | Middlesex | United Kingdom | Recruiting |
| Queen Alexandra Hospital Coordinator of this site? Confirm its status | Portsmouth | United Kingdom | Recruiting |
| Salisbury District Hospital Coordinator of this site? Confirm its status | Salisbury | United Kingdom | Recruiting |
| University Hospital of North Tees Coordinator of this site? Confirm its status | Stockton-on-Tees | United Kingdom | Recruiting |
| Royal Marsden Hospital Coordinator of this site? Confirm its status | Sutton | United Kingdom | Recruiting |
| Musgrove Park Hospital Coordinator of this site? Confirm its status | Taunton | United Kingdom | Recruiting |
| Croydon University Hospital Coordinator of this site? Confirm its status | Thornton Heath | United Kingdom | Recruiting |
| University Hospital of South Manchester & Manchester Royal Infirmary Coordinator of this site? Confirm its status | Wythenshawe | United Kingdom | Recruiting |
| Yeovil District Hospital Coordinator of this site? Confirm its status | Yeovil | United Kingdom | Active, not recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.