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NCT02259218Completed

Metabolomic and Epigenetic Profiling of Bodyfluids From Lung and Brain Cancer Receiving Radiation Therapy

Biomarker Discovery for Toxicity and Survival in Radiation Oncology: An Integrative Molecular-Clinical Approach

Source: ClinicalTrials.gov · Last updated 13 Apr 2026

Brief summary (registry, in English)

This research trial studies metabolomic and other molecular profiling to identify predictive biomarkers for radiation toxicity and survival in patients with lung or brain cancers receiving radiation therapy. Studying samples of blood, urine, and tissue from patients with lung or brain cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer and predict which patients are at higher risk for developing radiation side effects and how well patients will respond to radiation treatment.

Status (registry)
Completed
Study type
Observational
Enrollment
273 (actual)
First submitted
11 Sept 2014
Start date
4 Oct 2012
Primary completion date
17 Sept 2025
Lead sponsor
Ohio State University Comprehensive Cancer Center
Diseases
Lung cancer
NCT number
NCT02259218

What you commit to

  • Study type: Observational
  • Participants enrolled: 273
  • From 4 Oct 2012 to the primary completion date, 17 Sept 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Being an inmate

Who the study is looking for

  • Consultation with the Radiation Oncology department of the Ohio State University (OSU) Comprehensive Cancer Center
  • The following diagnoses will be included: malignant neoplasm of the brain; primary malignant neoplasm of trachea bronchus and lung; primary malignant neoplasm of the cervix uteri and primary malignant neoplasm the prostate

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center
Coordinator of this site? Confirm its status
ColumbusUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.