NCT02263274Completed
Direct Cortical Measurement of the Intensity and Pattern of Current Flow Produced by TDCS
Source: ClinicalTrials.gov · Last updated 27 Feb 2026
Brief summary (registry, in English)
The primary study objective is to measure the electrical fields evoked by tDCS using subjects who have implanted intracranial electrodes as part of their evaluation for epilepsy surgery. The measurements obtained in these subjects and their brain MRI will be employed to validate existing mathematical models. In the future, these refined models can be used to target tDCS to predetermined brain regions in healthy and subjects and patient populations. As described above in the safety section, the intensities of stimulation applied in this project are not expected to produce changes in brain function, are below intensities commonly applied in clinical trials, and fall well below safety limits suggested by animal studies.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 8 Oct 2014
- Start date
- 1 Nov 2013
- Primary completion date
- 9 Jan 2026
- Lead sponsor
- NYU Langone Health
- Diseases
- Epilepsy
- NCT number
- NCT02263274
What you commit to
- Study type: Interventional
- Participants enrolled: 30
- From 1 Nov 2013 to the primary completion date, 9 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Space occupying intracranial pathology including brain tumor, ateriovenous malformation, cavernous malformation, prior surgical resection or significant encephalomalcia that would create unknown tissue inhomogeneity that cannot be accurately modeled.
- Subjects who have had an electrographic or clinical seizure within one hour prior to the stimulation procedure
Other illness
- Cognitive impairment (Intelligence Quotient \<70)
- Known adhesive allergy
Other
- Facial or forehead skin breakdown that would interfere with surface electrode placement
- Contraindication to MRI
Who the study is looking for
- Subjects for this study will be recruited from patients undergoing routine intracranial electrode placement as part of the evaluation for surgical treatment of medically refractory epilepsy. Inclusion criteria include:
- Age ≥ 18 years
- Placement of intracranial electrode arrays (grid, strip and or depth electrodes) for seizure focus localization and/or mapping of eloquent cortex
- Able to provide written informed consent
- English-speaking patients only
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Neurology Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.