NCT02292641Recruiting
Beyond TME Origins
Investigating the Origins of Pelvic Recurrence in Colorectal Cancer
Source: ClinicalTrials.gov · Last updated 17 Oct 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
All patients with recurrent colorectal cancer in the pelvis are eligible. The original primary tumour staging scans and resected surgical specimen needs to be available. Patients' recurrence will be staged using our proposed MRI classification. We will be assessing the original primary staging scans and histopathology to learn about risk factors for recurrence. We will record treatment for the recurrence, and patients will be followed up for three years.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 383 (estimated)
- First submitted
- 2 May 2014
- Start date
- 25 Sept 2014
- Primary completion date
- Dec 2026
- Lead sponsor
- Imperial College London
- Diseases
- Colorectal cancer, Childhood cancers
- NCT number
- NCT02292641
What you commit to
- Study type: Interventional
- Planned participants: 383
- From 25 Sept 2014 to the primary completion date, Dec 2026
- 4 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Original preoperative, surgical and adjuvant treatment has not been documented or is unavailable
Other illness
- Have irresectable extra-pelvic metastatic disease
- Original baseline staging and preoperative restaging scans (MR for rectal and sigmoid cancers and/or CT for colon and sigmoid cancers) are unavailable
Who the study is looking for
- Had a primary colorectal adenocarcinoma proven by biopsy taken as part of routine clinical practice
- Has a confirmed diagnosis of recurrent pelvic colorectal cancer
- Has previously completed surgical treatment of primary adenocarcinoma of the colon, sigmoid colon or rectum
- Are able to undergo high resolution MRI for staging prior to treatment decisions
- Have provided written informed consent to participate in the study
- Be aged 16 years or over
Age in the registry: 16 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St Mark's Hospital Coordinator of this site? Confirm its status | Harrow | United Kingdom | Recruiting |
| Churchill Hospital Coordinator of this site? Confirm its status | Oxford | United Kingdom | Recruiting |
| Royal Marsden Hospital NHS Foundation Trust Coordinator of this site? Confirm its status | Sutton | United Kingdom | Recruiting |
| Oslo University Hospital Coordinator of this site? Confirm its status | Oslo | Norway | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.