NCT02302742Recruiting
Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry
PROspective Evaluation of GErmline Mutations, Cancer Outcome and Tissue Biomarkers: A Registry for Patients With Triple Negative Breast Cancer and Germline Mutations
Source: ClinicalTrials.gov · Last updated 18 Aug 2026
Brief summary (registry, in English)
PROGECT is a registry for patients with Triple Negative breast cancer (TNBC) or patients who have an identified germline mutations (such as a mutation on the BRCA1 or BRCA2 genes).
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 3000 (estimated)
- First submitted
- 11 Nov 2014
- Start date
- 22 Mar 2011
- Primary completion date
- Dec 2026
- Lead sponsor
- University of Kansas Medical Center
- NCT number
- NCT02302742
What you commit to
- Study type: Observational
- Planned participants: 3000
- From 22 Mar 2011 to the primary completion date, Dec 2026
- 11 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Triple Negative Breast Cancer -Patient is not within five years of diagnosis
Other
- Germline mutation Carriers:
- -Patient only carries a HBOC mutation that is classified as "polymorphism" of "favor polymorphism"
Who the study is looking for
- Triple Negative Breast Cancer
- ER/PR \<10% and HER negative per current ASCO/CAP guidelines
- Stages I-IV
- Any age at diagnosis
- Patient must be within 5 years of diagnosis
- Eligible regardless of genetic testing status
- Genetic testing recommended for patients meeting NCCN and Medicare guidelines
- AND/OR
- Germline mutation Carriers
- Patients with deleterious or uncertain mutations in HBOC genes (BRCA, PTEN, P53, -PALB2 etc) are eligible regardless of type/site of cancer
- Healthy patients harboring mutations also eligible
- There is no time limit from the time of diagnosis of cancer and enrollment.
- Eligible regardless of personal history of cancer
Sex: All · Accepts healthy volunteers
Sites (11)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hays Medical Center Dreiling-Schmidt Cancer Institute Coordinator of this site? Confirm its status | Hays | United States | Recruiting |
| Universtiy Health Coordinator of this site? Confirm its status | Kansas City | United States | Recruiting |
| Research Medical Center Coordinator of this site? Confirm its status | Kansas City | United States | Recruiting |
| KCCC South Coordinator of this site? Confirm its status | Kansas City | United States | Recruiting |
| KCCC - North Coordinator of this site? Confirm its status | Kansas City | United States | Recruiting |
| KCCC West Coordinator of this site? Confirm its status | Kansas City | United States | Recruiting |
| KCCC Lee's Summit Coordinator of this site? Confirm its status | Lee's Summit | United States | Recruiting |
| Overland Park Regional Medical Center Coordinator of this site? Confirm its status | Overland Park | United States | Recruiting |
| KCCC Overland Park Coordinator of this site? Confirm its status | Overland Park | United States | Recruiting |
| Salina Regional Health Center - Tammy Walker Cancer Center Coordinator of this site? Confirm its status | Salina | United States | Recruiting |
| The University of Kansas Cancer Center Coordinator of this site? Confirm its status | Westwood | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.