NCT02344680Completed
Liver Fibrosis in Zambian HIV-HBV Co-infected Patients
Liver Fibrosis in Zambian HIV-HBV Co-infected Patients: a Long-term Prospective Cohort Study
Source: ClinicalTrials.gov · Last updated 2 Jul 2026
Brief summary (registry, in English)
A cohort of adults with HIV-HBV co-infection will be created in Lusaka, Zambia, to describe the short and long-term (up to 10 years of follow-up) HBV and liver outcomes, including the effectiveness of current therapies, and to identify the risk factors for major endpoints of interest, including HCC and HBV functional cure. This cohort will also create a pool of potential participants for in-depth mechanistic studies and clinical trials of novel HBV cure drugs.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 349 (actual)
- First submitted
- 12 Jan 2015
- Start date
- 1 Oct 2015
- Primary completion date
- 28 May 2026
- Lead sponsor
- University of Alabama at Birmingham
- Diseases
- HIV, Liver and biliary tract cancer
- NCT number
- NCT02344680
What you commit to
- Study type: Observational
- Participants enrolled: 349
- From 1 Oct 2015 to the primary completion date, 28 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Unable or unwilling to provide informed consent
- Planning to relocate out of Lusaka district
Who the study is looking for
- Age 18 years or older
- Living with HIV infection
- Living with active HBV infection, defined as any single positive HBsAg assay
- Naïve to antiretroviral therapy or currently participating in HIV/HBV co-infection in IeDEA-SA
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre for Infectious Disease Research in Zambia (CIDRZ) Coordinator of this site? Confirm its status | Lusaka | Zambia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.