NCT02382822Active, not recruiting
Copenhagen Comorbidity in HIV Infection Study
Source: ClinicalTrials.gov · Last updated 12 Aug 2026
Brief summary (registry, in English)
Despite efficient antiretroviral treatment for HIV infection, decrease in life expectancy remains. Excess mortality is mainly due to non-AIDS co-morbidity including cardiovascular, pulmonary, and liver related diseases. Both HIV-unrelated and HIV-related risk factors probably contribute to this pattern. At present, most evidence regarding co-morbidity in HIV infection rely on cross-study comparisons of HIV-infected persons with published population rates and few prospective studies in U.S. cohorts. Using well characterized participants from the Copenhagen General Population Study (CGPS) as controls, we aim to include \>1500 HIV-infected persons in the COCOMO study to determine if co-morbidity is more prevalent or develops at a higher rate in HIV-infected persons. The study will asses 1) cardiovascular, 2) pulmonary and 3) liver-related co-morbidity using uniformly collected data in the two cohorts. The investigators aim to study the relative impact of HIV-unrelated and HIV-related factors on development of co-morbidity.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 1099 (actual)
- First submitted
- 3 Mar 2015
- Start date
- 1 Feb 2015
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Susanne Dam Nielsen, MD, DMSc
- NCT number
- NCT02382822
What you commit to
- Study type: Observational
- Participants enrolled: 1099
- From 1 Feb 2015 to the primary completion date, 31 Dec 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- relative contraindications to spirometry (i.e. chest, abdominal or eye surgery within the 3 months before baseline spirometry, and known retinal detachment)
- Implants (e.g. pacemaker, coclea implants, insulin pumps)
Other illness
- contraindications to CT and contrast (i.e. pregnancy, renal impairment, allergy to contrast media, allergy or contraindication to beta blocking agent, body weight more than 120kg, evidence of ongoing myocardial ischemia, heart rhythm precluding EKG gating)
- Spirometry:
- allergy or contraindications to salbutamol (i.e. \>110 bpm, or a known uncontrolled cardiac condition (i.e. unstable coronary artery disease, decompensated heart failure)
- a respiratory illness with at least two symptoms of breathlessness, cough, wheezing, or increase in sputum production within 6 weeks.
- MRI:
- Risk of bleeding
- Infection in puncture site
Other
- patients that are unable to understand information material
- Computed tomography (CT):
- Claustrophobia
- Pregnancy
- Liver Biopsy:
Who the study is looking for
- signed informed consent
- HIV infected
- aged 20-100 years
Age in the registry: 20 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Copenhagen University Hospital, Rigshospitalet Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Copenhagen University Hospital - Amager and Hvidovre Coordinator of this site? Confirm its status | Hvidovre | Denmark | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.