NCT02414022Active, not recruiting
Economic Analysis of Alliance A041202 CLL Study
Prospective Economic Analysis: A Randomized Phase III CLL Study of Bendamustine Plus Rituximab Versus Ibrutinib + Rituximab vs Ibrutinib Alone in Untreated Older Patients (≥65 Years of Age) With Chronic Lymphocytic Leukemia (CLL)
Source: ClinicalTrials.gov · Last updated 30 Jun 2026
Brief summary (registry, in English)
The prospective cost-effectiveness (cost-utility) analysis from the perspective of the Canadian public healthcare system was completed in 2021. Health state utilities were collected using the EuroQOL EQ-5D instrument with Canadian tarrifs applied to calculate quality-adjusted life-years (QALYs). Costs were applied to resource utilization data (expressed in 20196 US dollars). We examined costs and outcomes (QALYs) associated with ibrutinib with rituximab (IR) and BR therapy.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 55 (actual)
- First submitted
- 7 Apr 2015
- Start date
- 15 Apr 2015
- Primary completion date
- 5 Apr 2019
- Lead sponsor
- Canadian Cancer Trials Group
- Diseases
- Chronic lymphocytic leukaemia
- NCT number
- NCT02414022
What you commit to
- Study type: Observational
- Participants enrolled: 55
- From 15 Apr 2015 to the primary completion date, 5 Apr 2019
- 15 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- None
Who the study is looking for
- Patient must be eligible for the core CLC.2/A041202 protocol.
- Patient consent must be appropriately obtained in accordance with applicable local and regulatory requirements. Each patient must sign a consent form prior to enrollment in the trial to document their willingness to participate.
- Patient must be able (i.e. sufficiently fluent), and willing to complete the health utilities questionnaire in English or French. The baseline assessment must be completed within required timelines, prior to registration/randomization Inability (illiteracy in English or French, loss of sight, or other equivalent reason) to complete the questionnaires will not make the patient ineligible for the core protocol. However, ability but unwillingness to complete the questionnaires will make the patient ineligible for the core protocol.
- Patients must be accessible for treatment and follow-up. Investigators must assure themselves the patients randomized on this trial will be available for complete documentation of the treatment, adverse events, and follow-up.
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (15)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tom Baker Cancer Centre Coordinator of this site? Confirm its status | Calgary | Canada | Unknown status |
| Health Sciences North Coordinator of this site? Confirm its status | Greater Sudbury | Canada | Unknown status |
| CSSS Champlain-Charles LeMoyne Coordinator of this site? Confirm its status | Greenfield Park | Canada | Unknown status |
| Juravinski Cancer Centre at Hamilton Health Sciences Coordinator of this site? Confirm its status | Hamilton | Canada | Unknown status |
| Kingston Health Sciences Centre Coordinator of this site? Confirm its status | Kingston | Canada | Unknown status |
| London Regional Cancer Program Coordinator of this site? Confirm its status | London | Canada | Unknown status |
| The Moncton Hospital Coordinator of this site? Confirm its status | Moncton | Canada | Unknown status |
| CHUM - Centre Hospitalier de l'Universite de Montreal Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| The Jewish General Hospital Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| Stronach Regional Health Centre at Southlake Coordinator of this site? Confirm its status | Newmarket | Canada | Unknown status |
| Ottawa Hospital Research Institute Coordinator of this site? Confirm its status | Ottawa | Canada | Unknown status |
| Allan Blair Cancer Centre Coordinator of this site? Confirm its status | Regina | Canada | Unknown status |
| University Health Network - Princess Margaret Cancer Centre Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| Odette Cancer Centre, Sunnybrook Health Sciences Centre Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| Humber River Hospital Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.