NCT02427269Enrolling by invitation
University of North Carolina (UNC) Barrett's Esophagus and Esophageal Cancer Biorepository
UNC Barrett's Esophagus and Esophageal Cancer Biorepository
Source: ClinicalTrials.gov · Last updated 24 Jun 2026
Brief summary (registry, in English)
Aim 1: To develop a prospective tissue and blood biorepository from patients with a history of Barrett's Esophagus (BE) or esophageal cancer (ECA) presenting to UNC hospitals for routine care upper endoscopy for their condition. Aim 2: To collect clinical data from patients with a history of Barrett's Esophagus (BE) or esophageal cancer (ECA) that includes demographic data, endoscopic procedure data, and pathology data. Aim 3: To integrate Aim 1 and 2 in a manner that will provide an efficient bi-directional flow of clinical information and specimens between laboratory and clinical scientists in order to foster innovative translational research. Aim 4: To create a biorepository for future Institutional Review Board (IRB) approved studies that have tissue and/or blood specimen component.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 22 Apr 2015
- Start date
- 28 Apr 2015
- Primary completion date
- 31 May 2028
- Lead sponsor
- University of North Carolina, Chapel Hill
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT02427269
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 28 Apr 2015 to the primary completion date, 31 May 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current use of blood thinners such as coumadin, warfarin, clopidogrel, heparin and/or low molecular weight heparin (requires discontinuation of medication 5 days prior to and 6 days after esophagogastroduodenoscopy \[EGD\] and/or ensuring blood thinners have been stopped within an appropriate time frame for that specific agent and in accordance with standard clinical practice).
Other illness
- Known bleeding disorder.
Other
- Unable to read or understand English.
- Current incarceration.
Who the study is looking for
- Male or female aged 18 and older.
- Able to read, comprehend, and complete the informed consent form.
- Presenting to UNC hospitals for routine care upper endoscopy for their condition.
- Meet one of the following:
- Current or previous diagnosis of Barrett's Esophagus (BE) with or without dysplasia OR
- Current or previous diagnosis of esophageal cancer (including esophageal adenocarcinoma, intramucosal carcinoma, and squamous cell carcinoma)
- Willing to undergo biopsy and blood collection for research purposes.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UNC- Chapel Hill Coordinator of this site? Confirm its status | Chapel Hill | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.