NCT02432560Recruiting
Safety and Durability of Sirolimus for Treatment of LAM
Multicenter International Durability and Safety of Sirolimus in LAM Trial (MIDAS)
Source: ClinicalTrials.gov · Last updated 24 Dec 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The MIDAS study aims to follow male and female LAM patients who are currently taking, have previously failed or been intolerant of, or may (at some time in the future) take mTOR inhibitors (sirolimus or everolimus) as part of their clinical care. Adult female TSC patients may also enroll, with or without lung cysts.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 4 Mar 2015
- Start date
- 1 Mar 2015
- Primary completion date
- 31 Jul 2025
- Lead sponsor
- University of Cincinnati
- NCT number
- NCT02432560
What you commit to
- Study type: Observational
- Planned participants: 600
- From 1 Mar 2015 to the primary completion date, 31 Jul 2025
- 20 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Inability to attend at least one RLD Clinic visit per year
- Inability to give informed consent
- Inability or unwillingness to perform pulmonary function testing
Who the study is looking for
- Female or male, age 18 or over
- Diagnosis of LAM based on ATS/JRS criteria
- Signed and dated informed consent
- On chronic therapy, newly treated or may be considered for therapy with mTOR inhibitors or previously intolerant of or having failed mTOR inhibitor therapy
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (20)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Michigan Coordinator of this site? Confirm its status | Ann Arbor | United States | Recruiting |
| Emory University School of Medicine Coordinator of this site? Confirm its status | Atlanta | United States | Recruiting |
| Brigham and Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| Medical University of South Carolina Coordinator of this site? Confirm its status | Charleston | United States | Active, not recruiting |
| University of Cincinnati Coordinator of this site? Confirm its status | Cincinnati | United States | Active, not recruiting |
| Cleveland Clinic Coordinator of this site? Confirm its status | Cleveland | United States | Active, not recruiting |
| University of Texas Southwestern Medical Center Coordinator of this site? Confirm its status | Dallas | United States | Active, not recruiting |
| National Jewish Health Coordinator of this site? Confirm its status | Denver | United States | Recruiting |
| University of Texas Health Center Coordinator of this site? Confirm its status | Houston | United States | Active, not recruiting |
| Mayo Clinic- Jacksonville Coordinator of this site? Confirm its status | Jacksonville | United States | Recruiting |
| Loyola University Medical Center, Chicago Coordinator of this site? Confirm its status | Maywood | United States | Active, not recruiting |
| Vanderbilt University Medical Center Coordinator of this site? Confirm its status | Nashville | United States | Active, not recruiting |
| University of Pennsylvania Medical Center Coordinator of this site? Confirm its status | Philadelphia | United States | Active, not recruiting |
| Oregon Health and Science University Coordinator of this site? Confirm its status | Portland | United States | Active, not recruiting |
| University of Rochester Medical Center Coordinator of this site? Confirm its status | Rochester | United States | Recruiting |
| Mayo Clinic - Rochester Coordinator of this site? Confirm its status | Rochester | United States | Active, not recruiting |
| University of Utah School of Medicine Coordinator of this site? Confirm its status | Salt Lake City | United States | Active, not recruiting |
| Swedish Medical Center Coordinator of this site? Confirm its status | Seattle | United States | Active, not recruiting |
| Stanford University Medical Center Coordinator of this site? Confirm its status | Stanford | United States | Recruiting |
| Washington University School of Medicine Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.