NCT02439060Completed
PUBMIC (Prophylactic Use of Biologic Mesh in Ileal Conduit)
Prevention of Parastomal Hernia Following Radical Cystectomy and Ileal Conduit Using Biologic Mesh: Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 23 Apr 2025
Brief summary (registry, in English)
This randomized phase III trial studies how well biologic mesh works in preventing parastomal hernia in patients with bladder cancer who are undergoing radical cystectomy, or removal of the bladder, and ileal conduit diversion. An ileal conduit is a tube created from your small intestine that will be used as a tube for urine to flow out of your body. Parastomal hernia is a type of hernia that can occur in the stomach area where the ileal conduit is placed. Biologic mesh may help prevent parastomal hernia following surgery and ileal conduit diversion.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 156 (actual)
- First submitted
- 6 May 2015
- Start date
- 25 Nov 2015
- Primary completion date
- 7 Jun 2024
- Lead sponsor
- University of Southern California
- Diseases
- Bladder cancer, Childhood cancers
- NCT number
- NCT02439060
What you commit to
- Study type: Interventional
- Participants enrolled: 156
- From 25 Nov 2015 to the primary completion date, 7 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous scar or mesh at the level of ileal conduit
- Survival less than 12 months after surgery (either predicted survival before surgery or actual survival after surgery \< 12 months)
Other illness
- History of allergic reactions attributed to compounds of similar chemical or biologic composition to cadaveric component, i.e. Flex HD
Who the study is looking for
- Bladder cancer, undergoing radical cystectomy and ileal conduit diversion
- Ability to understand and the willingness to sign a written informed consent
- Follow-up either here at University of Southern California (USC) or centers that are available to transfer the requested clinical and radiological data
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| USC / Norris Comprehensive Cancer Center Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.