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NCT02496273Active, not recruitingPhase 1

Phase I Trial of CEA Specific AAV-DC-CTL Treatment in Stage IV Gastric Cancer

Phase 1 Study of CEA Specific Cytotoxic T Lymphocytes Induced by Dendritic Cells Infected by Recombinant Adeno-associated Virus With CEA Gene in Stage IV Gastric Cancer

Source: ClinicalTrials.gov · Last updated 22 Feb 2016

Brief summary (registry, in English)

The purpose of this study is to evaluate the clinical safety and preliminary efficacy of CEA specific cytotoxic T lymphocytes induced by dendritic cells infected by recombinant adeno-associated virus with CEA gene in the treatment of stage IV gastric cancer patients.

Status (registry)
Active, not recruiting
Phase (registry)
Phase 1
Study type
Interventional
Enrollment
60 (estimated)
First submitted
9 Jul 2015
Start date
1 Jan 2016
Primary completion date
31 Dec 2026
Lead sponsor
The First People's Hospital of Changzhou
NCT number
NCT02496273

What you commit to

  • Study type: Interventional · Phase 1
  • Planned participants: 60
  • From 1 Jan 2016 to the primary completion date, 31 Dec 2026
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients receiving systemic corticosteroid within 48 hours of CTL infusion.

Other illness

  • Patients with severe active infection.
  • Patients with HBV,HCV,HIV infection.

Who the study is looking for

  • Any patient, at least 18 yrs old regardless of sex, with a diagnosis of Stage IV Gastric Cancer
  • Patients with life expectancy greater than or equal to 6 weeks.
  • Patients with a Karnofsky score of greater than or equal to 80.
  • serum CEA ≥ 20ng/ml.
  • Patient provides consent for all required biopsies.

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.