NCT02511288Recruiting
LIquid BIopsies in Patients Presenting Non-small Cell Lung Cancer
Liquid Biopsies in Patients With Advanced Non-small Cell Lung Cancer
Source: ClinicalTrials.gov · Last updated 21 Aug 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this project is to characterize the genetic profile of patients with advanced stage IIIB/IV non-small cell lung cancer (NSCLC) using liquid biopsies
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 900 (estimated)
- First submitted
- 16 Jul 2015
- Start date
- Jul 2015
- Primary completion date
- Mar 2026
- Lead sponsor
- Centre Leon Berard
- Diseases
- Lung cancer
- NCT number
- NCT02511288
What you commit to
- Study type: Observational
- Planned participants: 900
- From Jul 2015 to the primary completion date, Mar 2026
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Inclusion at the time of immunotherapy treatment initiation (1st or 2nd line)
Lab values
- Patients with histologically confirmed advanced non-small-cell lung carcinoma (stage IIIB/IV) with one of the following molecular anomalies: Epidermal Growth Factor Receptor (EGFR), B-Raf proto oncogene (BRAF) or Human Epidermal Growth Factor Receptor-2 (HER2) mutations, Anaplatsic Lymphoma Kinase (ALK) or ROS porto-oncogene 1 (ROS1) translocation, Mesenchymal-epithelial transition factor (MET) amplification, RET rearrangement.
Age
- Age ≥ 18 years
- Age ≥ 18 years
Other
- \- Patients treated before their liquid biopsy
- COHORT 2 Inclusion criteria
- Inclusion at the time of diagnosis
- Realization of tumor biopsy at the institution (Centre Léon Bérard) or outside the institution with an available histopathological report
- Covered by a health insurance
- Signed consent
- COHORT 3 Inclusion criteria
- Patients with histologically confirmed advanced non-small-cell lung carcinoma (stage IIIB/IV) whatever the mutational or PD-L1 status.
- Realization of tumor biopsy at the institution (Centre Léon Bérard) or outside the institution with an available histopathological report
- Covered by a health insurance
- Signed consent
- \- Initiation of immunotherpy before their liquid biopsy
Who the study is looking for
- Patients with histologically confirmed advanced non-small-cell lung carcinoma (stage IIIB/IV) regardless of the mutation status
- Inclusion at the time of diagnostic
- Realization of tumor biopsy at the institution (Centre Léon Bérard) or outside the institution with an available histopathological report
- Age ≥ 18 years
- Covered by a health insurance
- Signed consent
Criteria the registry did not label
- COHORT 1
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier Annecy Genevois Coordinator of this site? Confirm its status | Annecy | France | Active, not recruiting |
| CH Fleyriat Coordinator of this site? Confirm its status | Bourg-en-Bresse | France | Active, not recruiting |
| Hôpital Louis Pradel Coordinator of this site? Confirm its status | Bron | France | Active, not recruiting |
| CHU Grenoble Alpes Coordinator of this site? Confirm its status | Grenoble | France | Active, not recruiting |
| Centre Leon Berard Coordinator of this site? Confirm its status | Lyon | France | Recruiting |
| CHRU de Saint-Etienne Coordinator of this site? Confirm its status | Saint-Priest-en-Jarez | France | Active, not recruiting |
| Institut de Cancérologie Lucien Neuwirth Coordinator of this site? Confirm its status | Saint-Priest-en-Jarez | France | Active, not recruiting |
| Hôpital Nord Ouest Coordinator of this site? Confirm its status | Villefranche-sur-Saône | France | Active, not recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.