NCT02592356Completed
Effect of Cabozantinib S-Malate or Lenvatinib Mesylate on Weight and Body Composition in Patients With Metastatic Endocrine Cancer
Effects of Tyrosine Kinase Inhibitors on Body Composition in Endocrine Tumors -- A Pilot Study
Source: ClinicalTrials.gov · Last updated 5 Mar 2024
Brief summary (registry, in English)
The goal of this clinical research study is to learn about possible weight, muscle, and/or fat loss in patients receiving cabozantinib or lenvatinib.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 23 (actual)
- First submitted
- 27 Oct 2015
- Start date
- 16 Nov 2015
- Primary completion date
- 1 Mar 2024
- Lead sponsor
- M.D. Anderson Cancer Center
- Diseases
- Thyroid cancer
- NCT number
- NCT02592356
What you commit to
- Study type: Interventional
- Participants enrolled: 23
- From 16 Nov 2015 to the primary completion date, 1 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Active participation in any weight reduction program including use of drugs used for weight loss
Other
- Inability to ambulate without assistance (e.g. cane, walker)
- Multiple Endocrine Neoplasia (MEN) 2B (due to differences in body habitus)
- Patients unwilling or unable to comply with the protocol.
- Use of chronic (\>3 months consecutively) non-physiological (15 mg/m² hydrocortisone equivalent) doses of glucocorticoids
- Non-English speaking PH and PG patients
Who the study is looking for
- Age \>/= 18 years
- Initiating cabozantinib for progressive DTC, MTC, malignant PH or PGs or lenvatinib for progressive DTC or MTC as determined by patient's endocrinologist
- ECOG performance status 0-2
- Able to communicate in English or Spanish
- Able to provide informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| M D Anderson Cancer Center Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.