NCT02600156Completed
Focal Laser Ablation of Low to Intermediate Prostate Cancer Tumors
A Pilot Study to Evaluate Magnetic Resonance Thermal Image-Guided Focal Laser Ablation of Prostate Cancer Tumors
Source: ClinicalTrials.gov · Last updated 17 Dec 2025
Brief summary (registry, in English)
The primary purpose of this study is to evaluate the feasibility and safety of MRI-guided focal laser ablation (Laser-Induced Interstitial Thermal Therapy, LITT) to treat low-risk native prostate cancer.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 7 (actual)
- First submitted
- 4 Sept 2015
- Start date
- 1 Sept 2015
- Primary completion date
- 20 Aug 2025
- Lead sponsor
- Mayo Clinic
- Diseases
- Prostate cancer
- NCT number
- NCT02600156
What you commit to
- Study type: Interventional
- Participants enrolled: 7
- From 1 Sept 2015 to the primary completion date, 20 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of other primary non-skin malignancy within previous three years.
Other illness
- Presence of any condition (e.g., metal implant, shrapnel) not compatible with MRI.
Who the study is looking for
- Male, 45 years of age or older.
- Diagnosis of prostate adenocarcinoma.
- Clinical stage T1c or T2a.
- Gleason score of 7 (3+4 or 4+3) or Intermediate risk Gleason 6
- PSA less than or equal to 20 ng/mL
- Three or fewer biopsy locations with prostate cancer which correlate with MRI findings.
- No lesion \> or = 2cm
- One, two, or three tumor suspicious regions identified on multiparametric MRI
- No definite radiographic indication of extra-capsular extension.
- Estimated survival of 5 years or greater, as determined by treating physician.
- Tolerance for anesthesia/sedation.
- Ability to give informed consent.
Age in the registry: 45 years to - · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic in Minnesota Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.