NCT02600208Active, not recruitingPhase 2
Peripheral Blood Stem Cell Transplantation for Hematologic Malignancies With Alpha Beta TCell and B Cell Depletion Using the CliniMACS Device
BT13BTθ51 Unrelated and Partially Matched Related Donor Peripheral Stem Cell Transplantation With Alpha Beta T Cell and B Cell Depletion For Patients With Hematologic Malignancies
Source: ClinicalTrials.gov · Last updated 1 May 2026
Brief summary (registry, in English)
This is a single arm pilot study for patients with hematologic malignancies with alternative donor sources receiving unrelated or partially matched related/Haploidentical mobilized peripheral stem cells (PSCs) using the CliniMACS system for Alpha Beta T cell depletion plus CD19+ B cell depletion to determine efficacy as determined by engraftment and GVHD, and one year leukemia free survival.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 28 Oct 2015
- Start date
- Oct 2015
- Primary completion date
- Dec 2026
- Lead sponsor
- Julie-An M. Talano
- Diseases
- Childhood cancers
- NCT number
- NCT02600208
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 60
- From Oct 2015 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patient
- Patients who do not meet disease, organ or infectious criteria.
- No suitable donor
Who the study is looking for
- Patient:
- Age. Patient age \< 23 years. Both genders and all races eligible.
- Disease eligibility
- Leukemias/lymphomas:
- Acute myeloid leukemia, primary or secondary
- Disease status: remission or \<10% bone marrow blasts
- Myelodysplasia
- Acute lymphoblastic leukemia
- Disease status: in hematologic remission
- Chronic myelogenous leukemia:
- Disease status: chronic phase, accelerated phase or blast crisis now in second chronic phase.
- Mixed lineage or biphenotypic acute leukemia
- Lymphoblastic lymphoma
- Disease status: remission
- Burkitt's lymphoma/leukemia:
- Disease status: in remission
Age in the registry: - to 23 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Hospital of Wisconsin Coordinator of this site? Confirm its status | Milwaukee | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.