NCT02662907Active, not recruiting
Cough, Expiratory Training, and Chronic Aspiration After Head and Neck Radiotherapy
Source: ClinicalTrials.gov · Last updated 7 Oct 2026
Brief summary (registry, in English)
The goal of this clinical research study is to learn if exercising the muscles that help you cough and swallow, called expiratory muscle strength training (EMST), can help reduce the risk of pneumonia due to aspiration (inhaling saliva instead of swallowing it) in patients who have had radiation for head and neck cancer.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 175 (actual)
- First submitted
- 14 Jan 2016
- Start date
- 1 Feb 2016
- Primary completion date
- 2 Feb 2027
- Lead sponsor
- M.D. Anderson Cancer Center
- Diseases
- Head and neck cancer
- NCT number
- NCT02662907
What you commit to
- Study type: Interventional
- Participants enrolled: 175
- From 1 Feb 2016 to the primary completion date, 2 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior H\&N surgery excluding diagnostic procedures, transoral surgery, or non-radical neck dissection
Other illness
- History of recurrent or second primary H\&N, central nervous system, or thoracic cancer at time of modified barium swallow (MBS) study
- History of functionally limiting chronic or acute cardiac, pulmonary, or neuromuscular disease
Other
- Tracheotomy or oxygen dependence at time of MBS
- Patients with Mini-Mental State Examination (MMSE) \<24 will be ineligible for participation in the therapeutic trial
Who the study is looking for
- Age \>/= 18 years
- History of curative-intent radiotherapy at MDACC for a new primary H\&N cancer in past 15 years
- Referred to Section of Speech Pathology and Audiology for swallowing evaluation
- Ability to understand and willingness to sign written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Texas - MD Anderson Cancer Center Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.