NCT02670447Recruiting
Early Identification of Patients Presenting a First Psychotic Episode, Non Answering to First Line Support Strategies
Early Identification of Patients Presenting a First Psychotic Episode, Non Answering to First Line Support Strategies: A Multicentric Study
Source: ClinicalTrials.gov · Last updated 22 Sept 2026
Brief summary (registry, in English)
Researchers propose in this project to evaluate predictive factors of non response. It is defined by the lack of symptomatic remission at month 3, for patients presenting a first episode of psychosis. It will be performed on objective markers taken from imagery techniques. The link between evolution of these markers and clinical measures will be studied.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 80 (estimated)
- First submitted
- 28 Jan 2016
- Start date
- 11 Dec 2025
- Primary completion date
- 30 Apr 2030
- Lead sponsor
- Centre Hospitalier Universitaire de Saint Etienne
- Diseases
- Schizophrenia
- NCT number
- NCT02670447
What you commit to
- Study type: Observational
- Planned participants: 80
- From 11 Dec 2025 to the primary completion date, 30 Apr 2030
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Female patients of childbearing period without effective contraception (oral, intramuscular hormonal, intrauterine device, or surgical);
- Participating in another clinical trial or being in an exclusion period of the previous protocol;
Other illness
- Presenting a serious somatic or neurological disease, especially Parkinson's disease, epilepsy, debilitating tardive dyskinesia, cardiovascular disease, severe liver or kidney;
- Featuring against-indication for an MRI; including: metallic foreign body eye or intracranial, pacemaker, heart valve, surgical clips, claustrophobia, large tattoo in the upper part of the body, not compatible with 3T MRI
- Having a history of alcohol or drug abuse in the past year;
Other
- Patients pregnant or nursing;
- Patients likely to exhibit aggressive behavior self according to the judgment of the investigators.
Who the study is looking for
- men and women aged 18-35 years
- member or beneficiary of a social security scheme,
- for women, appropriate contraception will be mandatory, as well as a negative pregnancy test,
- patients with a diagnosis of schizophrenia, schizoaffective disorder or schizophreniform disorder according to the DMS V
- having never received anti-psychotic treatment,
- followed in the hospital or outpatient,
- having given their written informed consent,
- that the physical examination revealed no significant clinical abnormalities
Age in the registry: 18 years to 35 years · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chu Le Vinatier Coordinator of this site? Confirm its status | Bron | France | Not yet recruiting |
| CHU Clermont-Ferrand Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Not yet recruiting |
| Chu Grenoble Coordinator of this site? Confirm its status | Grenoble | France | Not yet recruiting |
| Hopital Edouard Herriot Coordinator of this site? Confirm its status | Lyon | France | Not yet recruiting |
| CHU Saint-Etienne Coordinator of this site? Confirm its status | Saint-Etienne | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.