NCT02701153Recruiting
Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort
Source: ClinicalTrials.gov · Last updated 10 Mar 2026
Brief summary (registry, in English)
This phase II trial studies the side effects of hypofractionated radiation therapy in treating patients with soft tissue sarcomas prior to surgery. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 51 (estimated)
- First submitted
- 2 Mar 2016
- Start date
- 3 Feb 2016
- Primary completion date
- 3 Feb 2027
- Lead sponsor
- Jonsson Comprehensive Cancer Center
- Diseases
- Sarcoma
- NCT number
- NCT02701153
What you commit to
- Study type: Interventional
- Planned participants: 51
- From 3 Feb 2016 to the primary completion date, 3 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of prior irradiation to the area to be treated
- Pre-operative chemotherapy (post-op acceptable)
Other illness
- Active treatment of a separate malignancy
Who the study is looking for
- Histologically confirmed soft tissue sarcoma of the extremity/trunk
- Intermediate or high grade sarcoma
- Resectable primary lesion (patients with pre-existing metastasis will be included if their primary is still going to be resected)
- Recurrent, any grade, no previous radiation therapy
- Karnofsky performance status (KPS) \>= 70 or Eastern Cooperative Oncology Group (ECOG) 0 - 2
- If a woman is of childbearing potential, a negative serum pregnancy test must be documented
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UCLA / Jonsson Comprehensive Cancer Center Coordinator of this site? Confirm its status | Los Angeles | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.