NCT02775227Active, not recruitingPhase 4
HYPAR Trial - Hydrocortisone vs. Pasireotide in Reducing Pancreatic Surgery Complications
HYPAR Trial - Hydrocortisone vs Pasireotide in Reducing Pancreatic Fistula and Other Complications After Pancreatic Resection - a Prospective, Randomized, Controlled Trial
Source: ClinicalTrials.gov · Last updated 24 Aug 2020
Brief summary (registry, in English)
Pancreatic resections carry a high risk for complications, especially pancreatic fistula. Both hydrocortisone and pasireotide have been shown to be effective in reducing complications in earlier RCTs. The aim of this study is to compare the effectiveness and safety of these two drugs in preventing complications of pancreatic surgery.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 126 (actual)
- First submitted
- 14 May 2016
- Start date
- May 2016
- Primary completion date
- Jan 2019
- Lead sponsor
- Helsinki University Central Hospital
- Diseases
- Pancreatic cancer
- NCT number
- NCT02775227
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 126
- From May 2016 to the primary completion date, Jan 2019
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Allergy or other contraindication for hydrocortisone or pasireotide
- Pancreatic resection cancelled (e.g. disseminated cancer)
Age
- Age \< 18 years
Other
- Preoperative exclusion criteria:
- Atrophic pancreas and/or dilated pancreatic duct at the site of planned pancreatic transsection (applies only to patients undergoing pancreaticoduodenectomy)
- Total pancreatectomy planned
- No informed consent
- Intraoperative exclusion criteria:
- Hard pancreas and/or dilated pancreatic duct discovered during operation (applies only to patients undergoing pancreaticoduodenectomy)
- Total pancreatectomy is performed
Who the study is looking for
- Patients scheduled for pancreatic surgery (pancreaticoduodenectomy, distal pancreatectomy, enucleation, or other type of pancreatic resection)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Helsinki University Central Hospital Coordinator of this site? Confirm its status | Helsinki | Finland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.