NCT02776969Completed
A Gene Hunting Study for Familial Papillary Thyroid Cancer
A Strategy to Search for Genes Predisposing to Papillary Carcinoma of the Thyroid When Mutated
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
The aim of this project is to identify genetic risk factors associated with familial papillary thyroid carcinoma (PTC). Papillary thyroid cancer is a type of cancer that shows high heritability. However, the specific genetic factors that cause an increased risk have been elusive.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1200 (estimated)
- First submitted
- 12 May 2016
- Start date
- 5 Aug 1998
- Primary completion date
- 9 Feb 2025
- Lead sponsor
- Ohio State University Comprehensive Cancer Center
- Diseases
- Thyroid cancer
- NCT number
- NCT02776969
What you commit to
- Study type: Observational
- Planned participants: 1200
- From 5 Aug 1998 to the primary completion date, 9 Feb 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Known germline predisposition (ex: pathogenic PTEN variant)
- Non-English speaking
Who the study is looking for
- Patients with a diagnosis of PTC and a family history of PTC in 3 or more living relatives
- Affected and unaffected family members of the proband\*
- For familial cases (families with 4 or more cases of PTC), participation will be offered to all living family members with PTC or benign thyroid disease as well as selected unaffected first and second degree relatives. Participation may also be offered to spouses when needed for analyzing parent/offspring samples.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ohio State University Comprehensive Cancer Center Coordinator of this site? Confirm its status | Columbus | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.