NCT02791152Recruiting
Effects of Physical Activity, Ambulatory Blood Pressure and Calcium Score on Cardiovascular Health in Normal People
SingHEART: Effects of Physical Activity, Ambulatory Blood Pressure and Calcium Score on Cardiovascular Health in Normal People
Source: ClinicalTrials.gov · Last updated 6 Jun 2016 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
A prospective cohort of relatively healthy individuals, using comprehensive clinical information, advanced imaging (including cardiac MRI), cardiovascular exercise physiology, metabolomics and genetic analysis. These findings will be correlated with adverse clinical outcomes including death, stroke and myocardial infarction. In selected cases, follow-up imaging and biomarker samples will also be obtained. These studies will enable us to begin to address a critical gap in our knowledge as to how best to interpret the very large amount of cardiovascular tests done in Singapore and how to better to predict outcomes and manage healthcare costs in our local populations
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 31 May 2016
- Start date
- Oct 2015
- Primary completion date
- Dec 2036
- Lead sponsor
- National Heart Centre Singapore
- Diseases
- Coronary artery disease
- NCT number
- NCT02791152
What you commit to
- Study type: Observational
- Planned participants: 1000
- From Oct 2015 to the primary completion date, Dec 2036
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous myocardial infarction (MI). This will include ST-elevation MI (STEMI) and non-ST-elevation MI (NSTEMI)
- Known coronary artery disease - prior coronary revascularization
- Previous stroke
- Stroke is defined as new focal neurological deficit persisting more than 24hours21.
Other illness
- Known documented peripheral arterial disease
- Prior history of cancer (excludes pre-cancerous lesions)
- Known definite diabetes mellitus or on treatment for diabetes mellitus
- Known autoimmune disease or genetic disease
- Known endocrine disease on treatment
- Psychiatric illness
- Asthma or chronic lung disease requiring long term medications or oxygen
- Chronic infective disease, including tuberculosis, hepatitis B and C; and HIV
- Any other acute or chronic medical or physical condition deemed by the investigator to affect study outcomes
Other
- More than ongoing use of 2 or more anti-hypertensive agents
- Expected life expectancy less than 1 year
- Inability to comply with study protocol
Who the study is looking for
- Men and women age 21-69 years
Age in the registry: 21 years to 69 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Heart Centre Singapore Coordinator of this site? Confirm its status | Singapore | Singapore | Recruiting |
Related publications
- Unexpected genotypes associated with severe paediatric conditions identified in a healthy population cohort.Eur J Hum Genet · 2026 · PMID 41520097
This page is information, not medical advice. Discuss any trial with your doctor.