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NCT02811653Recruiting

Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease

Source: ClinicalTrials.gov · Last updated 28 May 2026

Brief summary (registry, in English)

In AD (Alzheimer disease), the anatomic correlates of attention disorders (as evaluated by motor slowing) have not been thoroughly characterized.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
155 (estimated)
First submitted
16 Jun 2016
Start date
Dec 2015
Primary completion date
Dec 2028
Lead sponsor
Centre Hospitalier Universitaire, Amiens
NCT number
NCT02811653

What you commit to

  • Study type: Interventional
  • Planned participants: 155
  • From Dec 2015 to the primary completion date, Dec 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Past or present neurological disorders other than those having prompted consultation in the Memory Clinic:
    • stroke.
    • meningitis or encephalitis.
    • severe head injury.
    • sensorimotor impairments (sensory, proprioceptive, cerebellar and visual impairments).
    • epilepsy (requiring ongoing treatment),
    • psychiatric disorders (other than treated depression).
    • treatment with psychotropic medications (other than anxiolytics or antidepressant withdrawn or initiated in the previous month). Patients with parkinsonian syndrome were examined in the "on-drug" state.
  • Contra-indication to MRI:
    • nerve stimulators
    • cochlear implants
    • ferromagnetic foreign bodies close to nervous structures in the eye or brain
    • cerebral shunts
    • dental appliances

Other illness

  • Reading or writing difficulties related to a learning disorder or illiteracy.
  • A medical history with a potentially significant impact on cognition (non-corrected thyroid disorders or heart failure):
    • NYHA stage IV dyspnoea.
    • respiratory impairment requiring oxygen therapy.
    • liver impairment.
    • kidney failure, progressing neoplastic disease, or past or present alcohol abuse.

Other

  • Impossibility to perform a neuropsychological evaluation or brain MRI.
  • Withdrawal from the study at any time, if desired.
  • Pregnancy
  • Legal guardianship or incarceration.

Who the study is looking for

  • Patients
    • Age between 40 and 85
    • French mother tongue
    • Consulting at the Amiens Memory Resource and Research Centre (CMRR) for:
    • MCI, according to Albert et al.'s criteria (Albert et al., 2011)
    • Mild dementia (MMSE\>20) due to AD, according to McKhann's criteria (McKhann et al., 2011).
    • Mild dementia due to LBD, according to McKeith et al.'s criteria (McKeith et al., 2005).
    • Mild dementia due to FTLD, according to Rascovsky et al.'s criteria (Rascovsky et al., 2011).
    • Social security coverage
  • Healthy controls
    • Healthy age and gender matched volunteers will be recruited into the study from the general population.

Age in the registry: 40 years to 85 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
CHU Amiens
Coordinator of this site? Confirm its status		AmiensFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.