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NCT02818517Recruiting

Evaluation and Management of Cardio Toxicity in Oncologic Patients

Source: ClinicalTrials.gov · Last updated 2 Feb 2022 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

The survival rate of cancer patients has greatly increased over the past decades' mainly due to early detection and the use of new medications with higher doses and combined protocols. This achievement comes with the price of cardio toxicity, leading to cardiac dysfunction ranged from transient asymptomatic left ventricular dysfunction to cardiac death. In the long term, the risk of death from cardiovascular causes exceeds that of tumor recurrence for many types of cancer. As a result of the increasing number of long-term cancer survivors the magnitude of this problem is growing. Early identification of cardio toxicity can be identified by clinical follow-up and the use of electrocardiography, cardiac biomarkers (Troponin, brain natriuretic peptide) and echocardiogram. Past studies imply that the addition of angiotensin-converting-enzyme inhibitor (ACE inhibitor) and beta blockers to the patient's treatment may prevent the development of cardiac dysfunction. However, currently there are no specific or clear guidelines for the follow-up and management of cardio-toxicity in cancer patients. The aim of the study: To try to identify who are the patients at increased risk for developing cardio toxicity, by follow up of clinical evaluation, cardiac biomarkers and echocardiogram examination, in purpose of early diagnosis, management and prevention of cardiac events. For achieving this the investigators will build a registry which will include all the oncologic patients going an evaluation in the cardio-oncology clinic in the Tel Aviv Medical Center .

Status (registry)
Recruiting
Study type
Observational
Enrollment
1000 (estimated)
First submitted
15 Jun 2016
Start date
1 Aug 2016
Primary completion date
30 Nov 2030
Lead sponsor
Tel-Aviv Sourasky Medical Center
NCT number
NCT02818517

What you commit to

  • Study type: Observational
  • Planned participants: 1000
  • From 1 Aug 2016 to the primary completion date, 30 Nov 2030
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • In the prospective Study - patients not sign an informed consent form.
  • Patient reluctance to continue the study.

Who the study is looking for

  • All patient evaluated in the cardio-oncology clinic in Tel Aviv MC

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Tel Aviv Medical Center
Coordinator of this site? Confirm its status
Tel AvivIsraelRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.