NCT02874040Completed
Endoresection of the Tumor Scar or Transpupillary Thermotherapy for the Treatment of Large Uveal Melanomas (Endoresection-Laser)
Phase II Evaluating Endoresection of the Tumor Scar or Transpupillary Thermotherapy When Endoresection is Not Feasible After Proton Beam Therapy for the Treatment of Large Uveal Melanomas
Source: ClinicalTrials.gov · Last updated 8 Aug 2025
Brief summary (registry, in English)
Study the efficacy of endoresection of the tumor scar or, when surgery is not possible, transpupillary thermotherapy on the tumor scar to prevent neovascular glaucoma and secondary enucleation
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 87 (actual)
- First submitted
- 11 Aug 2016
- Start date
- 19 Apr 2013
- Primary completion date
- 24 Oct 2023
- Lead sponsor
- Institut Curie
- Diseases
- Melanoma
- NCT number
- NCT02874040
What you commit to
- Study type: Interventional
- Participants enrolled: 87
- From 19 Apr 2013 to the primary completion date, 24 Oct 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with glaucoma before the radiation therapy
Other
- Massive extrascleral extension posterior to the equator
- Patients with metastasis at diagnosis.
- Patients with opaque media preventing transpupillary thermotherapy
- Patients for whom follow up will be difficult due to geographical, social or psychological reasons
Who the study is looking for
- Tumor of 7 mm of thickness or more
- Patients treated by proton beam therapy
- Patients aged at least 18 years
- Patients clearly informed of the study, having received the letter of information and signed the consent
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institut Curie Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.