NCT02931513Recruiting
sCD163 in PBC Patients - Assessment of Treatment Response
Macrophage Activation Marker sCD163 in PBC Patients - Assessment of Treatment Response to UDCA
Source: ClinicalTrials.gov · Last updated 12 Aug 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Primary biliary cholangitis (PBC) is an autoimmune chronic liver disease, characterised by destruction of the small intrahepatic bile ducts. Ursodeoxycholic acid (UDCA) is the first line treatment for patients with PBC. However, up to 40% of patients respond inadequate to this treatment. sCD163 is a macrophage activation marker shedded into plasma by macrophages in the liver. sMR is a soluble mannose receptor. The investigators want to investigate whether sCD163 and sMR can predict response to treatment with UDCA in newly diagnosed patients with PBC.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 40 (estimated)
- First submitted
- 11 Oct 2016
- Start date
- Sept 2016
- Primary completion date
- Jan 2031
- Lead sponsor
- University of Aarhus
- Diseases
- Primary biliary cholangitis
- NCT number
- NCT02931513
What you commit to
- Study type: Observational
- Planned participants: 40
- From Sept 2016 to the primary completion date, Jan 2031
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Expected liver transplantation within 6 months
Other illness
- Liver cancer
Other
- Patient under 18 years
- Expected lifetime under 6 months
- Cirrhosis from other causes
Who the study is looking for
- Newly diagnosed with Primary biliary cholangitis
- No treatment with UDCA
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Hepatology and Gastroenterology, Aarhus University Hospital, Denmark Coordinator of this site? Confirm its status | Aarhus C | Denmark | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.