NCT02938481Completed
International Prospective Observational Cohort Study for Optimal Bowel Resection Extent and Central Radicality for Colon Cancer
Source: ClinicalTrials.gov · Last updated 29 Jan 2026
Brief summary (registry, in English)
The T-REX study aims to clarify the actual status of metastatic lymph node (LN) distribution in colon cancer and provide reliable evidence regarding the optimal length of bowel resection and the extent of central lymph node dissection in colon cancer surgery.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 3647 (actual)
- First submitted
- 17 Oct 2016
- Start date
- 30 May 2013
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
- Diseases
- Colorectal cancer, Childhood cancers
- NCT number
- NCT02938481
What you commit to
- Study type: Observational
- Participants enrolled: 3647
- From 30 May 2013 to the primary completion date, 31 Dec 2023
- 36 sites in 7 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- All patients with preoperative adjuvant therapy
Other illness
- Tis (mucosal cancer)
- Multiple colon cancers
Who the study is looking for
- Histologically proven colon adenocarcinoma
- Pathological stage Ⅰ, Ⅱ or Ⅲ
- Potentially curative surgery
- Informed consent for observational data collection
Sex: All · Does not accept healthy volunteers
Sites (36)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Erlangen Coordinator of this site? Confirm its status | Erlangen | Germany | Unknown status |
| University of Leeds Coordinator of this site? Confirm its status | Leeds | United Kingdom | Unknown status |
| Tokyo Medical and Dental University Coordinator of this site? Confirm its status | Bunkyo-ku | Japan | Unknown status |
| Tokyo Metropolitan Cancer and Infectious Disease Centre Komagome Hospital Coordinator of this site? Confirm its status | Bunkyo-ku | Japan | Unknown status |
| National Canser Centre Hospital East Coordinator of this site? Confirm its status | Chiba | Japan | Unknown status |
| National Cancer Centre Central Hospital Coordinator of this site? Confirm its status | Chuo-ku | Japan | Unknown status |
| Teikyo University Chiba Medical Center Coordinator of this site? Confirm its status | Ichihara-shi | Japan | Unknown status |
| Saitama Cancer Center Coordinator of this site? Confirm its status | Kitaadachi-gun | Japan | Unknown status |
| Takano Hospital Coordinator of this site? Confirm its status | Kumamoto | Japan | Unknown status |
| Kurume University School of Medicine Coordinator of this site? Confirm its status | Kurume | Japan | Unknown status |
| Kyorin University School of Medicine Coordinator of this site? Confirm its status | Mitaka | Japan | Unknown status |
| Aichi Cancer Centre Hospital Coordinator of this site? Confirm its status | Nagoya | Japan | Unknown status |
| Niigata Cancer Center Hospital Coordinator of this site? Confirm its status | Niigata | Japan | Unknown status |
| Osaka International Cancer Institute Coordinator of this site? Confirm its status | Osaka | Japan | Unknown status |
| Shiga University of Medical Science Coordinator of this site? Confirm its status | Ōtsu | Japan | Unknown status |
| Keiyukai Sapporo Hospital Coordinator of this site? Confirm its status | Sapporo | Japan | Unknown status |
| Tokyo Women's Medical University Coordinator of this site? Confirm its status | Shinjuku-ku | Japan | Unknown status |
| Shizuoka Cancer Centre Hospital Coordinator of this site? Confirm its status | Sunto-gun | Japan | Unknown status |
| Teikyo University School of Medicine Coordinator of this site? Confirm its status | tabashi City | Japan | Unknown status |
| National Defense Medical College Coordinator of this site? Confirm its status | Tokorozawa | Japan | Unknown status |
| Fujita Health University Coordinator of this site? Confirm its status | Toyoake | Japan | Unknown status |
| Mie University Graduate School of Medicine Coordinator of this site? Confirm its status | Tsu | Japan | Unknown status |
| Tochigi Cancer Center Coordinator of this site? Confirm its status | Utsunomiya | Japan | Unknown status |
| Wakayama Medical University Coordinator of this site? Confirm its status | Wakayama | Japan | Unknown status |
| Yamagata Prefectural Central Hospital Coordinator of this site? Confirm its status | Yamagata | Japan | Unknown status |
| Kanagawa Cancer Centre Hospital Coordinator of this site? Confirm its status | Yokohama | Japan | Unknown status |
| Yokohama-city University Coordinator of this site? Confirm its status | Yokohama | Japan | Unknown status |
| Yokohama City University Medical Center Coordinator of this site? Confirm its status | Yokohama | Japan | Unknown status |
| Saisei-kai Yokohama-shi Nanbu Hospital Coordinator of this site? Confirm its status | Yokohama | Japan | Unknown status |
| Yonsei University Coordinator of this site? Confirm its status | Seodaemun-gu | South Korea | Unknown status |
| University of Ulsan College of Medicine and Asan Medical Center Coordinator of this site? Confirm its status | Songpa-Gu | South Korea | Unknown status |
| Klaipeda University hospital Coordinator of this site? Confirm its status | Klaipėda | Lithuania | Unknown status |
| National Cancer Institute, Lithuania Coordinator of this site? Confirm its status | Vilnius | Lithuania | Unknown status |
| I.M. Sechenov First Moscow State Medical University Coordinator of this site? Confirm its status | Moscow | Russia | Unknown status |
| China Medical University Hospital Coordinator of this site? Confirm its status | Taichung | Taiwan | Unknown status |
| National Taiwan University Hospital Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.