NCT02938858Completed
French Registry of First-line Treatment of Acute Promyelocytic Leukemia
The French Registry on the First-line Treatment of Non High-risk Acute Promyelocytic Leukemia (APL) in Patients Aged ≤ 70 Years
Source: ClinicalTrials.gov · Last updated 11 Sept 2026
Brief summary (registry, in English)
The registry aims to compare the two first-line available treatment approaches in non-high-risk APL patients aged ≤ 70 years - ATRA plus chemotherapy and ATRA plus ATO - in terms of practitioner's choice between the two options, clinical effectiveness and cost-effectiveness, long-term outcome, and short- and long-term toxic effects.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 400 (actual)
- First submitted
- 22 Sept 2016
- Start date
- Oct 2015
- Primary completion date
- Jul 2026
- Lead sponsor
- Groupe Francophone des Myelodysplasies
- Diseases
- Acute myeloid leukemia, Childhood cancers
- NCT number
- NCT02938858
What you commit to
- Study type: Observational
- Participants enrolled: 400
- From Oct 2015 to the primary completion date, Jul 2026
- 27 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- Newly-diagnosed High-risk APL (White Blood Count \> 10000/μl at presentation)
Age
- Age \> 70 years
Other
- Relapsed APL
Who the study is looking for
- Newly-diagnosed APL (either de novo or therapy-related) based on cytologic criteria and confirmed by the presence of the t(15;17) translocation and/or by the detection of the fusion transcript PML/RARα.
- Non-high-risk APL (White Blood Count \< 10000/μl at presentation)
- Age ≤ 70 years
Age in the registry: - to 70 years · Sex: All · Does not accept healthy volunteers
Sites (27)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier d'Aix en Provence Coordinator of this site? Confirm its status | Aix-en-Provence | France | Unknown status |
| Groupe Hospitalier SUD Coordinator of this site? Confirm its status | Amiens | France | Unknown status |
| Centre Hospitalier V. Dupouy Coordinator of this site? Confirm its status | Argenteuil | France | Unknown status |
| Hopital Jean Minjoz Coordinator of this site? Confirm its status | Besançon | France | Unknown status |
| CHU Bordeaux Pellegrin enfant Coordinator of this site? Confirm its status | Bordeaux | France | Unknown status |
| CHRU de Brest - Pédiatrie Spécialisée Coordinator of this site? Confirm its status | Brest | France | Unknown status |
| CHU Estaing Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Unknown status |
| Hopital Henri Mondor Coordinator of this site? Confirm its status | Créteil | France | Unknown status |
| CHU de Grenoble Coordinator of this site? Confirm its status | Grenoble | France | Unknown status |
| Hôpital André Mignot Coordinator of this site? Confirm its status | Le Chesnay | France | Unknown status |
| CH Dr Schaffner Coordinator of this site? Confirm its status | Lens | France | Unknown status |
| CHRU, Hôpital Claude Huriez Coordinator of this site? Confirm its status | Lille | France | Unknown status |
| Hôpital Universitaire Dupuytren Coordinator of this site? Confirm its status | Limoges | France | Unknown status |
| Institut Paoli-Calmettes Coordinator of this site? Confirm its status | Marseille | France | Unknown status |
| Chu Timone Coordinator of this site? Confirm its status | Marseille | France | Unknown status |
| CHR Metz-Thionville - Hôpital de Marcy Coordinator of this site? Confirm its status | Metz | France | Unknown status |
| CHU Saint-Eloi Coordinator of this site? Confirm its status | Montpellier | France | Unknown status |
| CHU Hôtel Dieu Coordinator of this site? Confirm its status | Nantes | France | Unknown status |
| Hôpital de la Source Coordinator of this site? Confirm its status | Orléans | France | Unknown status |
| Hopital Robert Debre Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Hôpital Necker Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Hôpital Trousseau Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| CHU Hôpital Sud - service Hémato-oncologie Pédiatrique Coordinator of this site? Confirm its status | Rennes | France | Unknown status |
| Hôpital V. Provo Coordinator of this site? Confirm its status | Roubaix | France | Unknown status |
| Centre Henri Becquerel Coordinator of this site? Confirm its status | Rouen | France | Unknown status |
| Institut de Cancerologie de La Loire Coordinator of this site? Confirm its status | Saint-Priest-en-Jarez | France | Unknown status |
| IUCT Oncopôle Coordinator of this site? Confirm its status | Toulouse | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.