NCT02948972Recruiting
Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility
Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility: Complete Surgery + IVF Versus IVF (ENDOFERT)
Source: ClinicalTrials.gov · Last updated 22 Apr 2026
Brief summary (registry, in English)
The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 4 Oct 2016
- Start date
- 17 Nov 2016
- Primary completion date
- May 2026
- Lead sponsor
- University Hospital, Lille
- Diseases
- Endometriosis
- NCT number
- NCT02948972
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 17 Nov 2016 to the primary completion date, May 2026
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous IVF cycle(s)
- Previous colorectal surgery
- Need of myomectomy during surgery
Other
- Contraindication to pregnancy or to IVF
- Viral risk
- The use of oocytes donor
Who the study is looking for
- Primary and secondary infertility
- Indication for IVF
- Persistent pain related to endometriosis with analgesic medical treatment failure
- Persistent pain including at least one of the following digestive symptoms related to endometriosis: Dyschesia / Sub-occlusive syndrome / Rectal bleeding / Painful defecation
- Colorectal deep infiltrating endometriosis : Whatever lesion size / With at least rectal serosal involvement / Confirmed by MRI and 1 different investigation: vaginal ultrasound echography or coloscopic CT scan or rectal endoscope ultrasound
- Eligible for DIE surgery
Age in the registry: 18 years to 38 years · Sex: Female · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Recruiting |
| Hôpital Jeanne de Flandres, CHRU Coordinator of this site? Confirm its status | Lille | France | Recruiting |
| AP-HP - Hopital Tenon Coordinator of this site? Confirm its status | Paris | France | Recruiting |
| CHU Coordinator of this site? Confirm its status | Poissy | France | Recruiting |
| CHU Coordinator of this site? Confirm its status | Rouen | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.